Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 4/20 | 0.55 |
| ▸ | HTR1A | P08908 | 3/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 3/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | DRD5 | P21918 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8031034 | 0.85 | HTR1A (0.55) | DRD1HTR1AHIF1ASIRT6DRD2 | |
| SCHEMBL2272695 | 0.77 | HTR1A (0.47) | DRD1HTR1AHIF1ASIRT6CA1 | |
| SCHEMBL8015301 | 0.77 | HTR1A (0.52) | DRD1HTR1AHIF1ASIRT6DRD2 | |
| Hydrochloric Acid SCHEMBL7509854 | 0.75 | HTR1A (0.51) | DRD1HTR1AHIF1ASIRT6DRD2 | |
| SCHEMBL1950525 | 0.74 | PNMT (0.54) | DRD1HTR1AHIF1ASIRT6HTR2A | |
| SCHEMBL13900879 | 0.73 | DRD1 (0.71) | DRD1DRD2DRD4DRD5MAPK1 | |
| SCHEMBL3885369 | 0.72 | SIRT2 (0.55) | DRD1HTR1ASIRT6DRD4KMT2A | |
| SCHEMBL324724 | 0.72 | ADRA2A (0.51) | DRD1HTR1ASIRT6DRD2HTR2A | |
| SCHEMBL29558059 | 0.72 | ADRA2A (0.51) | DRD1HTR1ASIRT6DRD2HTR2A | |
| SCHEMBL20232216 | 0.71 | MAOA (0.50) | DRD1HTR1ASIRT6HTR2ADRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109689645-A | Cyanoindole quinoline derivant as NIK inhibitor | 杨森制药有限公司 | 2019-04-26 | — | — | CN | disclosed |