SCHEMBL5517520

SCHEMBL5517520

C=C(Cc1c(C)ccc2cc3ccccc3cc12)C(=O)O

nearest known ligand 0.37

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.37
KDM4E B2RXH2 4/20 0.37
HPGD P15428 4/20 0.37
HSD17B10 Q99714 3/20 0.37
KMT2A Q03164 3/20 0.37
MEN1 O00255 2/20 0.37
GLA P06280 2/20 0.37
CYP1A2 P05177 2/20 0.37
CYP2C19 P33261 1/20 0.37
GAA P10253 2/20 0.36
CASP1 P29466 1/20 0.35
AKR1B1 P15121 1/20 0.35
POLB P06746 1/20 0.33
GPR35 Q9HC97 1/20 0.33
PTGDR2 Q9Y5Y4 1/20 0.33
PTPN7 P35236 1/20 0.33
MAPT P10636 1/20 0.33
TSHR P16473 1/20 0.32
SLC22A12 Q96S37 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1497455 0.80 KDM4E (0.48) ALDH1A1KDM4EHPGDHSD17B10KMT2A
SCHEMBL2243225 0.76 TDP1 (0.49) ALDH1A1KDM4EHPGDHSD17B10KMT2A
SCHEMBL17697793 0.75 CYP1A2 (0.42) ALDH1A1KDM4EHPGDHSD17B10KMT2A
SCHEMBL9283073 0.74 KDM4E (0.40) ALDH1A1KDM4EHPGDHSD17B10KMT2A
SCHEMBL6677013 0.72 HTR2A (0.57) ALDH1A1KDM4EHPGDHSD17B10CYP1A2
Anthracene SCHEMBL1337867 0.71 ALDH1A1 (0.41) ALDH1A1KDM4EHPGDHSD17B10KMT2A
SCHEMBL3423595 0.71 MEN1 (0.41) ALDH1A1KDM4EKMT2AMEN1CYP1A2
Methacrylic Acid SCHEMBL6815378 0.71 ALDH1A1 (0.50) ALDH1A1KDM4EHPGDHSD17B10KMT2A
Methacrylic Acid SCHEMBL560416 0.71 ALDH1A1 (0.50) ALDH1A1KDM4EHPGDHSD17B10KMT2A
SCHEMBL350989 0.70 KDM4E (0.67) ALDH1A1KDM4EHPGDHSD17B10KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1309898-B1 ANTIREFLECTIVE COATING COMPOSITIONS SHIPLEY CO LLC (US) 2015-06-17 EP disclosed
US-7183037-B2 Antireflective coatings with increased etch rates SHIPLEY COMPANY, L.L.C. (US) 2007-02-27 US disclosed
EP-1309898-A2 ANTIREFLECTIVE COATING COMPOSITIONS Shipley Company LLC (US) 2003-05-14 EP disclosed
US-20020028408-A1 Etch resistant antireflective coating compositions SHIPLEY COMPANY, L.L.C. 2002-03-07 US disclosed
WO-2002014954-A2 ANTIREFLECTIVE COATING COMPOSITIONS SHIPLEY COMPANY, L.L.C. (US) 2002-02-21 WO disclosed