Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 6/20 | 0.42 |
| ▸ | PGR | P06401 | 4/20 | 0.42 |
| ▸ | HTR7 | P34969 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28296378 | 0.83 | DRD2 (0.38) | HTR7HTR1AHTR2ADRD3HTR6 | |
| SCHEMBL28296376 | 0.82 | NR3C1 (0.47) | NR3C1PGRHTR7HTR1AHTR2A | |
| SCHEMBL22273620 | 0.80 | NR3C1 (0.46) | NR3C1PGRHTR7HTR1AHTR2A | |
| SCHEMBL22273724 | 0.79 | RORC (0.46) | NR3C1PGRHTR7HTR1AHTR2A | |
| SCHEMBL28744878 | 0.78 | USP2 (0.55) | KMT2AHPGDLMNAALDH1A1GAA | |
| SCHEMBL29564093 | 0.78 | RORC (0.49) | NR3C1PGRHTR7HTR1AHTR2A | |
| SCHEMBL28941181 | 0.77 | NR3C1 (0.41) | NR3C1PGRHTR7HTR1AHTR2A | |
| SCHEMBL22273619 | 0.76 | NR3C1 (0.42) | NR3C1PGRHTR7HTR1AHTR2A | |
| SCHEMBL29563877 | 0.76 | RORC (0.42) | NR3C1PGRHTR7HTR1AHTR2A | |
| SCHEMBL22274053 | 0.75 | NR3C1 (0.42) | NR3C1PGRPOLBKMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109651297-A | A kind of N- benzyl-N- aryl sulfonic acid amides analog derivative and preparation and application | 杭州壹瑞医药科技有限公司 | 2019-04-19 | — | — | CN | claimed |
| CN-109651297-A | A kind of N- benzyl-N- aryl sulfonic acid amides analog derivative and preparation and application | 杭州壹瑞医药科技有限公司 | 2019-04-19 | — | — | CN | disclosed |