Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.38 |
| ▸ | DRD4 | P21917 | 5/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | HTR7 | P34969 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethoxycarbonyl Group SCHEMBL28296379 | 0.83 | HTR6 (0.37) | HSP90AA1ALDH1A1KDM4ELMNADRD3 | |
| SCHEMBL28294727 | 0.83 | NR3C1 (0.42) | ALDH1A1LMNADRD3HTR2AGAA | |
| SCHEMBL28744897 | 0.80 | MAPK1 (0.49) | ALDH1A1KDM4ELMNAGAAMAPT | |
| SCHEMBL28294730 | 0.76 | ALDH1A1 (0.53) | DRD2DRD4ALDH1A1KDM4ELMNA | |
| SCHEMBL28873296 | 0.71 | MAPT (0.50) | DRD2ALDH1A1KDM4ELMNADRD3 | |
| SCHEMBL28296408 | 0.70 | LTA4H (0.43) | DRD2DRD4ALDH1A1KDM4ELMNA | |
| SCHEMBL28296376 | 0.65 | NR3C1 (0.47) | ALDH1A1LMNADRD3HTR2AHTR7 | |
| SCHEMBL28294734 | 0.65 | LMNA (0.41) | DRD4ALDH1A1KDM4ELMNADRD3 | |
| SCHEMBL28744878 | 0.64 | USP2 (0.55) | ALDH1A1KDM4ELMNAGAAKMT2A | |
| SCHEMBL28744845 | 0.64 | MAPK1 (0.54) | ALDH1A1LMNAGAAMAPTRORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109651297-A | A kind of N- benzyl-N- aryl sulfonic acid amides analog derivative and preparation and application | 杭州壹瑞医药科技有限公司 | 2019-04-19 | — | — | CN | claimed |
| CN-109651297-A | A kind of N- benzyl-N- aryl sulfonic acid amides analog derivative and preparation and application | 杭州壹瑞医药科技有限公司 | 2019-04-19 | — | — | CN | disclosed |