Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMBS | P08397 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.32 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.32 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | ATP4A | P20648 | 2/20 | 0.30 |
| ▸ | ATP4B | P51164 | 2/20 | 0.30 |
| ▸ | TDO2 | P48775 | 1/20 | 0.30 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27643249 | 0.74 | ERCC1 (0.55) | HMBSERCC1ERCC4TDO2 | |
| SCHEMBL1525706 | 0.74 | CES2 (0.45) | ARAKR1C3RAPGEF4CES2CES1 | |
| SCHEMBL12583212 | 0.70 | RAPGEF4 (0.45) | RAPGEF4CES2CES1 | |
| SCHEMBL28240618 | 0.68 | NPC1 (0.47) | HMBSERCC1ERCC4 | |
| SCHEMBL10014275 | 0.67 | RAPGEF4 (0.42) | RAPGEF4CES2CES1 | |
| SCHEMBL10014228 | 0.67 | ACHE (0.43) | ARRAPGEF4 | |
| SCHEMBL16258106 | 0.67 | ACHE (0.43) | ARRAPGEF4 | |
| SCHEMBL8192072 | 0.67 | ACHE (0.43) | ARRAPGEF4 | |
| SCHEMBL13986747 | 0.67 | RAPGEF4 (0.42) | RAPGEF4CES2CES1 | |
| SCHEMBL28280408 | 0.67 | HMBS (0.48) | HMBSERCC1ERCC4NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109662961-A | For improving the method and composition of cognitive function | 约翰斯霍普金斯大学 | 2019-04-23 | — | — | CN | disclosed |