Known targets — ChEMBL curated mechanism
ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3CHRM1CHRM2CHRM3CHRM4ESR1ESR2GABRA1GABRB1GABRG2GBA1HRH1HTR1DHTR2AOPRD1OPRK1OPRM1SLC6A2SLC6A3TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Cadaverine Tartrate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.36 |
| ▸ | KLK7 | P49862 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 5/20 | 0.38 |
| ▸ | PPARA | Q07869 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chlorobenzene SCHEMBL27773693 | 0.92 | POLB (0.44) | KLK7POLBNPC1RAB9AALDH1A1 | |
| Chlorobenzene SCHEMBL27856994 | 0.90 | POLB (0.43) | KLK7POLBNPC1RAB9AALDH1A1 | |
| Cadaverine Tartrate SCHEMBL28295092 | 0.86 | KMT2A (0.39) | POLBSLC7A5NPC1RAB9AALDH1A1 | |
| Cadaverine Tartrate SCHEMBL28296886 | 0.84 | TSHR (0.46) | POLBSLC7A5LMNA | |
| Cadaverine Tartrate SCHEMBL28295190 | 0.82 | LTA4H (0.44) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| Biphenyl SCHEMBL3991647 | 0.77 | POLB (0.47) | POLBNPC1RAB9AALDH1A1MEN1 | |
| Toluene SCHEMBL27945492 | 0.75 | POLB (0.46) | POLBNPC1RAB9AALDH1A1MEN1 | |
| Phenol SCHEMBL27480309 | 0.75 | ESRRB (0.49) | POLBALDH1A1LMNA | |
| Chlorobenzene SCHEMBL7570717 | 0.75 | KLK7 (0.47) | KLK7POLBALDH1A1PTGS2MEN1 | |
| Chlorobenzene SCHEMBL27889729 | 0.75 | POLB (0.46) | KLK7POLBNPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114544851-A | Analysis method for determining o-chlorobenzene glycine methyl ester tartrate and impurities | 苏州正济医药研究有限公司 | 2022-05-27 | — | — | CN | claimed |
| CN-115326942-A | Analytical method for measuring p-toluenesulfonic acid thiophene ester | 苏州正济医药研究有限公司 | 2022-11-11 | — | — | CN | disclosed |
| CN-109867684-B | Preparation method of II-type clopidogrel hydrogen sulfate | 武汉武药制药有限公司 | 2022-06-17 | — | — | CN | disclosed |
| CN-114544851-A | Analysis method for determining o-chlorobenzene glycine methyl ester tartrate and impurities | 苏州正济医药研究有限公司 | 2022-05-27 | — | — | CN | disclosed |
| CN-114544851-A | Analysis method for determining o-chlorobenzene glycine methyl ester tartrate and impurities | 苏州正济医药研究有限公司 | 2022-05-27 | — | — | CN | disclosed |
| CN-109867685-B | Preparation method of clopidogrel hydrogen sulfate II type | 武汉武药制药有限公司 | 2022-04-08 | — | — | CN | disclosed |
| CN-109734617-A | A kind of method for splitting replacing aromatic ring phenylglycine aliphatic alcohol ester | 华东理工大学 | 2019-05-10 | — | — | CN | disclosed |