Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PRCP | P42785 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.34 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7995094 | 0.92 | ALDH1A1 (0.36) | GAAMAPTPRCPMTNR1AMTNR1B | |
| SCHEMBL6831393 | 0.80 | HTR2A (0.36) | MTNR1AMTNR1BALDH1A1OPRM1OPRK1 | |
| SCHEMBL10505998 | 0.75 | MAPT (0.47) | GAAMAPTPRCPMTNR1AMTNR1B | |
| SCHEMBL28873839 | 0.75 | GAA (0.39) | GAAMAPTGRIN2DGRIN3BGRIN1 | |
| SCHEMBL7099613 | 0.74 | GAA (0.36) | GAAMAPTMAPK1GRIN2DGRIN3B | |
| SCHEMBL30488180 | 0.72 | ALDH1A1 (0.39) | GAAMTNR1AMTNR1BTSHRMEN1 | |
| SCHEMBL9631444 | 0.70 | MAPT (0.47) | GAAMAPTTSHRGRIN2DGRIN3B | |
| SCHEMBL5319112 | 0.69 | SLC22A1 (0.50) | GAAMAPTPRCPMEN1KMT2A | |
| SCHEMBL3249767 | 0.69 | CYP2D6 (0.41) | GAAMAPTTSHRMEN1KMT2A | |
| SCHEMBL3240481 | 0.68 | PDE5A (0.37) | TSHRMEN1KMT2AALDH1A1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109790125-B | Tetrahydroisoquinoline kappa opioid antagonists | 研究三角协会 | 2022-07-05 | — | — | CN | claimed |
| CN-109790125-B | Tetrahydroisoquinoline kappa opioid antagonists | 研究三角协会 | 2022-07-05 | — | — | CN | disclosed |
| CN-109776414-A | A kind of Bcl-2 protein inhibitor and its preparation method and application | 山东大学 | 2019-05-21 | — | — | CN | disclosed |