SCHEMBL28296318

SCHEMBL28296318

CC(C)CCCC(C)Cc1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 6/20 0.48
TAAR1 Q96RJ0 4/20 0.48
SLC6A2 P23975 3/20 0.48
SLC6A4 P31645 2/20 0.48
SLC6A3 Q01959 2/20 0.48
MAOA P21397 1/20 0.48
CYP2A6 P11509 1/20 0.48
ADORA2A P29274 1/20 0.48
ADORA1 P30542 1/20 0.48
MEN1 O00255 1/20 0.47
ALDH1A1 P00352 1/20 0.47
HTT P42858 1/20 0.47
KMT2A Q03164 1/20 0.47
LMNA P02545 1/20 0.46
SLC18A2 Q05940 1/20 0.45
CYP2D6 P10635 1/20 0.45
TRPA1 O75762 2/20 0.44
EPHX1 P07099 1/20 0.41
ADRA2B P18089 1/20 0.41
ADRA2C P18825 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL28873017 0.98 SIGMAR1 (0.47) SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3
SCHEMBL7937685 0.83 TRPA1 (0.53) SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3
SCHEMBL6286870 0.83 SIGMAR1 (0.55) SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3
SCHEMBL6824286 0.83 CSNK1E (0.49) SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3
SCHEMBL5668643 0.82 LMNA (0.50) MEN1ALDH1A1HTTKMT2ALMNA
SCHEMBL9418115 0.82 SIGMAR1 (0.56) SIGMAR1
SCHEMBL6693090 0.82 CSNK1E (0.56) SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3
SCHEMBL4078807 0.82 SIGMAR1 (0.47) SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3
SCHEMBL19628486 0.82 TAAR1 (0.52) SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3
SCHEMBL11668767 0.80 TAAR1 (0.52) SIGMAR1TAAR1SLC6A2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109666792-A A kind of method of rare-earth extractant and rare-earth separating yttrium 厦门熙途科技有限公司 2019-04-23 CN disclosed