Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | MPO | P05164 | 1/20 | 0.31 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19996154 | 0.88 | HTR3A (0.41) | HTR3AHTR2CMPO | |
| SCHEMBL28296852 | 0.86 | HTR3A (0.38) | HTR3AHTR2CMPO | |
| SCHEMBL28296843 | 0.80 | HTR3A (0.38) | HTR3AHTR2CMPO | |
| SCHEMBL5542721 | 0.75 | HTR1A (0.42) | HTR2CSLC18A3SIGMAR1 | |
| SCHEMBL28298501 | 0.75 | HTR3A (0.56) | HTR3AHTR2CMPO | |
| SCHEMBL28873365 | 0.75 | HTR3A (0.43) | HTR3AHTR2CMPO | |
| SCHEMBL28298499 | 0.75 | HTR3A (0.43) | HTR3AHTR2CMPO | |
| SCHEMBL28296838 | 0.75 | HTR3A (0.43) | HTR3AHTR2CMPO | |
| SCHEMBL28296881 | 0.74 | HTR3A (0.42) | HTR3AHTR2C | |
| SCHEMBL19995575 | 0.73 | SLC6A2 (0.40) | HTR3AHTR2CMPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109715155-A | blood brain barrier-penetrating agent dopamine- β -hydroxylase inhibitors | 巴尔-波特拉及康邦亚股份有限公司 | 2019-05-03 | — | — | CN | disclosed |