Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 6/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | PTGES | O14684 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | PELI1 | Q96FA3 | 5/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28295273 | 0.76 | LTA4H (0.47) | XDHMEN1KMT2AKDM4EMAPT | |
| SCHEMBL28730603 | 0.75 | XDH (1.00) | XDHMEN1KMT2AKDM4EMAPT | |
| SCHEMBL29575725 | 0.75 | XDH (1.00) | XDHMEN1KMT2AKDM4EMAPT | |
| SCHEMBL29657650 | 0.75 | XDH (1.00) | XDHMEN1KMT2AKDM4EMAPT | |
| Rataniaphenol Ii SCHEMBL748016 | 0.71 | PTGES (1.00) | XDHMEN1KMT2AKDM4EMAPT | |
| Resveratrol SCHEMBL3704258 | 0.68 | PTGS1 (1.00) | MEN1KMT2AKDM4EMAPTALDH1A1 | |
| Resveratrol SCHEMBL20164915 | 0.68 | PTGS1 (1.00) | MEN1KMT2AKDM4EMAPTALDH1A1 | |
| Cis-Resveratrol SCHEMBL1931746 | 0.68 | PTGS1 (1.00) | MEN1KMT2AKDM4EMAPTALDH1A1 | |
| Resveratrol SCHEMBL17629801 | 0.68 | PTGS1 (1.00) | MEN1KMT2AKDM4EMAPTALDH1A1 | |
| Resveratrol SCHEMBL19426 | 0.68 | PTGS1 (1.00) | MEN1KMT2AKDM4EMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110433153-A | A kind of Amurensin H derivative is treating and preventing the application in liver related disease | INST MATERIA MEDICA CAMS | 2019-11-12 | — | — | CN | disclosed |
| CN-109893522-A | Amurensin H derivative is treating and preventing the application in Chronic Obstructive Pulmonary Disease | 中国医学科学院药物研究所 | 2019-06-18 | — | — | CN | disclosed |