Rataniaphenol Ii

Rataniaphenol Ii

SCHEMBL748016

C/C=C/c1ccc2oc(-c3ccc(O)cc3)c(C)c2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGES O14684 6/20 1.00
MEN1 O00255 6/20 1.00
KMT2A Q03164 6/20 1.00
ALDH1A1 P00352 4/20 1.00
KDM4E B2RXH2 3/20 1.00
MAPT P10636 3/20 1.00
HPGD P15428 3/20 1.00
MAPK1 P28482 3/20 1.00
SMN1; SMN2 Q16637 2/20 1.00
CYP3A4 P08684 4/20 0.43
CYP2C9 P11712 3/20 0.43
HSD17B10 Q99714 3/20 0.43
CYP2C19 P33261 2/20 0.40
TSHR P16473 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
XDH P47989 1/20 0.40
ALOX5 P09917 2/20 0.39
CNR2 P34972 1/20 0.38
CSNK2A2 P19784 1/20 0.38
CSNK2B P67870 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9669237 0.82 MEN1 (0.68) PTGESMEN1KMT2AALDH1A1KDM4E
SCHEMBL10334432 0.79 MAPT (0.65) PTGESMEN1KMT2AALDH1A1KDM4E
SCHEMBL29872579 0.76 MEN1 (0.60) PTGESMEN1KMT2AALDH1A1KDM4E
SCHEMBL18838053 0.76 PTGES (0.60) PTGESMEN1KMT2AALDH1A1KDM4E
SCHEMBL8164023 0.73 ALDH1A1 (0.56) PTGESMEN1KMT2AALDH1A1KDM4E
SCHEMBL15157440 0.73 ALDH1A1 (0.64) PTGESMEN1KMT2AALDH1A1KDM4E
SCHEMBL9136261 0.72 ALDH1A1 (0.63) PTGESMEN1KMT2AALDH1A1KDM4E
SCHEMBL30072406 0.71 PTGES (1.00) PTGESMEN1KMT2AALDH1A1KDM4E
SCHEMBL28297086 0.71 XDH (0.60) PTGESMEN1KMT2AALDH1A1KDM4E
SCHEMBL25327302 0.71 MAPT (0.72) PTGESMEN1KMT2AALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0930888-B1 PHARMACEUTICAL AND COSMETIC ANTIACNE FORMULATIONS CONTAINING PLANT EXTRACTS (KRAMERIA TRIANDRA OR MESUA FERREA) INDENA SPA (IT) 2002-06-05 EP claimed
EP-0932408-B1 PHARMACEUTICAL AND COSMETIC FORMULATIONS WITH ANTIMICROBIAL ACTIVITY INDENA SPA (IT) 2002-01-02 EP claimed
CN-1233183-A Pharmaceutical and cosmetic antiacne formulations containing plant extracts (Krameria triandra or mesua ferrea) INDENA SPA (IT) 1999-10-27 CN claimed
EP-0932408-A1 PHARMACEUTICAL AND COSMETIC FORMULATIONS WITH ANTIMICROBIAL ACTIVITY INDENA S.p.A. (IT) 1999-08-04 EP claimed
EP-0930888-A1 PHARMACEUTICAL AND COSMETIC ANTIACNE FORMULATIONS CONTAINING PLANT EXTRACTS (KRAMERIA TRIANDRA OR MESUA FERREA) INDENA S.p.A. (IT) 1999-07-28 EP claimed
WO-1998017294-A1 PHARMACEUTICAL AND COSMETIC FORMULATIONS WITH ANTIMICROBIAL ACTIVITY INDENA S.P.A. (IT) 1998-04-30 WO claimed
WO-1998017293-A1 PHARMACEUTICAL AND COSMETIC ANTIACNE FORMULATIONS CONTAINING PLANT EXTRACTS (KRAMERIA TRIANDRA OR MESUA FERREA) INDENA S.P.A. (IT) 1998-04-30 WO claimed
EP-0464297-B1 Complexes of neolignane derivatives with phospholipids, the use thereof and pharmaceutical and cosmetic formulations containing them INDENA SPA (IT) 1995-05-17 EP claimed
EP-0464297-A1 Complexes of neolignane derivatives with phospholipids, the use thereof and pharmaceutical and cosmetic formulations containing them INDENA S.p.A. (IT) 1992-01-08 EP claimed
US-20170304341-A1 METHODS FOR TREATING AND PREVENTING MUCOSITIS INDENA S.P.A. (IT) 2017-10-26 US disclosed
US-9730952-B2 Methods for treating and preventing mucositis INDENA S.P.A. (IT) 2017-08-15 US disclosed
US-8496975-B2 Compositions for the treatment and prevention of infections of the oral cavity INDENA S.P.A. (IT) 2013-07-30 US disclosed
EP-2522345-A1 Methods for treating and preventing mucositis INDENA S.p.A. (IT) 2012-11-14 EP disclosed
EP-2520295-A1 Methods for preventing and treating mucositis INDENA S.p.A. (IT) 2012-11-07 EP disclosed
EP-0932408-A1 PHARMACEUTICAL AND COSMETIC FORMULATIONS WITH ANTIMICROBIAL ACTIVITY INDENA S.p.A. (IT) 1999-08-04 EP disclosed
EP-0930888-A1 PHARMACEUTICAL AND COSMETIC ANTIACNE FORMULATIONS CONTAINING PLANT EXTRACTS (KRAMERIA TRIANDRA OR MESUA FERREA) INDENA S.p.A. (IT) 1999-07-28 EP disclosed
WO-1998017294-A1 PHARMACEUTICAL AND COSMETIC FORMULATIONS WITH ANTIMICROBIAL ACTIVITY INDENA S.P.A. (IT) 1998-04-30 WO disclosed
WO-1998017293-A1 PHARMACEUTICAL AND COSMETIC ANTIACNE FORMULATIONS CONTAINING PLANT EXTRACTS (KRAMERIA TRIANDRA OR MESUA FERREA) INDENA S.P.A. (IT) 1998-04-30 WO disclosed
EP-0464297-B1 Complexes of neolignane derivatives with phospholipids, the use thereof and pharmaceutical and cosmetic formulations containing them INDENA SPA (IT) 1995-05-17 EP disclosed
EP-0464297-A1 Complexes of neolignane derivatives with phospholipids, the use thereof and pharmaceutical and cosmetic formulations containing them INDENA S.p.A. (IT) 1992-01-08 EP disclosed