Methacrylic Acid

Methacrylic Acid

SCHEMBL28298434

C=C(C)C(=O)O.CCC(N)N(CC)CC.COC(Cl)c1ccccc1

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PGR P06401 1/20 0.35
ADRA2A P08913 1/20 0.35
ADRA2B P18089 1/20 0.35
HTR2A P28223 1/20 0.35
HRH1 P35367 1/20 0.35
KCNH2 Q12809 1/20 0.35
LMNA P02545 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2D6 P10635 1/20 0.34
ALDH1A1 P00352 3/20 0.33
HPGD P15428 1/20 0.33
CYP3A4 P08684 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
TSHR P16473 1/20 0.33
OPRD1 P41143 1/20 0.33
CHRM2 P08172 1/20 0.33
CHRM4 P08173 1/20 0.33
CHRM1 P11229 1/20 0.33
CHRM3 P20309 1/20 0.33
KDM4E B2RXH2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL28298451 0.89 AOC3 (0.35) KCNH2ALDH1A1HPGDKMT2AUTS2R
Methacrylic Acid SCHEMBL28298432 0.79 LMNA (0.44) ADRA2AKCNH2LMNACYP1A2CYP2D6
Methacrylic Acid SCHEMBL28298450 0.75 UTS2R (0.41) HTR2AHRH1LMNAALDH1A1SMN1; SMN2
Methacrylic Acid SCHEMBL6898658 0.73 PGR (0.43) PGRADRA2AADRA2BHTR2AHRH1
Methacrylic Acid SCHEMBL1989727 0.70 HPGD (0.48) HTR2AHRH1LMNACYP2D6HPGD
SCHEMBL105848 0.69 TSHR (0.50) ADRA2AADRA2BHTR2AHRH1KCNH2
SCHEMBL15974014 0.69 TSHR (0.50) ADRA2AADRA2BHTR2AHRH1KCNH2
Acrylic Acid SCHEMBL28058988 0.69 KMT2A (0.43) LMNACYP2D6ALDH1A1HPGDTSHR
SCHEMBL28058990 0.68 CHRM1 (0.49) ADRA2AADRA2BHTR2AHRH1KCNH2
Methacrylic Acid SCHEMBL28094452 0.68 PGR (0.32) PGRADRA2AADRA2BHTR2AHRH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109694603-A Foam fireproof coating 关西涂料株式会社 2019-04-30 CN disclosed