Methacrylic Acid

Methacrylic Acid

SCHEMBL28298432

C=C(C)C(=O)O.CCN(CC)CCCN.COC(Cl)c1ccccc1

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.44
CYP1A2 P05177 2/20 0.44
CYP2D6 P10635 2/20 0.44
ALDH1A1 P00352 3/20 0.43
CYP3A4 P08684 3/20 0.43
MAPT P10636 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
CHRM1 P11229 5/20 0.42
CHRM2 P08172 4/20 0.42
CHRM3 P20309 3/20 0.42
CHRM4 P08173 2/20 0.42
SIGMAR1 Q99720 1/20 0.40
KDM4E B2RXH2 2/20 0.39
KMT2A Q03164 1/20 0.38
HTR1A P08908 1/20 0.37
ADRA2A P08913 1/20 0.37
DRD1 P21728 1/20 0.37
SLC6A2 P23975 1/20 0.37
ADRA1A P35348 1/20 0.37
OPRM1 P35372 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL28298450 0.89 UTS2R (0.41) LMNAALDH1A1SMN1; SMN2CHRM1KDM4E
Methacrylic Acid SCHEMBL28298434 0.79 PGR (0.35) LMNACYP1A2CYP2D6ALDH1A1CYP3A4
Methacrylic Acid SCHEMBL28298451 0.78 AOC3 (0.35) ALDH1A1KMT2AKCNH2
Methacrylic Acid SCHEMBL6898657 0.77 LMNA (0.47) LMNACYP1A2CYP2D6ALDH1A1CYP3A4
SCHEMBL28058990 0.70 CHRM1 (0.49) LMNACYP1A2CYP2D6ALDH1A1CYP3A4
Bicarbonate SCHEMBL30077208 0.68 ALDH1A1 (0.43) LMNACYP1A2CYP2D6ALDH1A1CYP3A4
SCHEMBL105848 0.68 TSHR (0.50) LMNACYP1A2CYP2D6ALDH1A1SMN1; SMN2
SCHEMBL15974014 0.68 TSHR (0.50) LMNACYP1A2CYP2D6ALDH1A1SMN1; SMN2
Acrylic Acid SCHEMBL28058988 0.68 KMT2A (0.43) LMNACYP2D6ALDH1A1KMT2ATSHR
Methacrylic Acid SCHEMBL6898658 0.67 PGR (0.43) LMNACYP1A2CYP2D6ALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109694603-A Foam fireproof coating 关西涂料株式会社 2019-04-30 CN disclosed