Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | ABCC1 | P33527 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21192476 | 0.82 | CNR1 (0.44) | RAB9AALDH1A1ABCC1MAPK1HPGD | |
| SCHEMBL19993934 | 0.77 | ALDH1A1 (0.65) | RAB9AALDH1A1HPGDSMN1; SMN2TSHR | |
| SCHEMBL2807303 | 0.76 | ALDH1A1 (0.60) | RAB9AALDH1A1ABCC1RXFP1HPGD | |
| SCHEMBL28197452 | 0.76 | ALDH1A1 (0.45) | ALDH1A1ABCC1MAPK1RXFP1HPGD | |
| SCHEMBL28196740 | 0.76 | ABCC1 (0.43) | RAB9AALDH1A1ABCC1MAPK1HPGD | |
| SCHEMBL28196741 | 0.71 | LMNA (0.42) | ALDH1A1ABCC1HPGDSMN1; SMN2TSHR | |
| SCHEMBL8705267 | 0.71 | GRIN2C (0.40) | ALDH1A1ABCC1HPGDSMN1; SMN2TSHR | |
| SCHEMBL21980399 | 0.69 | ALDH1A1 (0.46) | RAB9AALDH1A1MAPK1HPGDSMN1; SMN2 | |
| SCHEMBL8290785 | 0.68 | ALDH1A1 (0.58) | RAB9AALDH1A1ABCC1MAPK1RXFP1 | |
| SCHEMBL5433835 | 0.64 | CNR1 (0.43) | RAB9AALDH1A1ABCC1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109963858-A | N3The thieno uracil and application thereof that ring-type replaces | 拜耳股份公司 | 2019-07-02 | — | — | CN | disclosed |