Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2C | Q14957 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | ANO1 | Q5XXA6 | 7/20 | 0.39 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | ANO2 | Q9NQ90 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2807303 | 0.80 | ALDH1A1 (0.60) | GRIN2CALDH1A1HPGDABCC1MAPT | |
| SCHEMBL28196741 | 0.78 | LMNA (0.42) | GRIN2CALDH1A1HPGDABCC1TP53 | |
| SCHEMBL28196740 | 0.73 | ABCC1 (0.43) | ALDH1A1HPGDABCC1TP53MAPT | |
| SCHEMBL28197452 | 0.73 | ALDH1A1 (0.45) | GRIN2CALDH1A1HPGDABCC1TP53 | |
| SCHEMBL4136897 | 0.73 | PKM (0.71) | ALDH1A1HPGDMAPTSMN1; SMN2TSHR | |
| SCHEMBL8290785 | 0.71 | ALDH1A1 (0.58) | ALDH1A1HPGDABCC1TP53MAPT | |
| SCHEMBL28298637 | 0.71 | RAB9A (0.43) | ALDH1A1HPGDABCC1MAPTSMN1; SMN2 | |
| SCHEMBL23413214 | 0.70 | GRIN2C (0.58) | GRIN2CALDH1A1HPGDABCC1TP53 | |
| SCHEMBL3723045 | 0.70 | GPR35 (0.39) | TRPM8 | |
| SCHEMBL20541969 | 0.68 | PTPN1 (0.67) | HPGDANO1ABCC1TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998054116-A1 | SYNTHESIS AND USE OF THIOPHENE- AND PYRROLE-BASED HETEROAROMATIC COMPOUNDS | CADUS PHARMACEUTICAL CORPORATION (US) | 1998-12-03 | — | — | WO | disclosed |