Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TRIM24 | O15164 | 4/20 | 0.42 |
| ▸ | BRD1 | O95696 | 3/20 | 0.42 |
| ▸ | BRPF1 | P55201 | 3/20 | 0.42 |
| ▸ | BRPF3 | Q9ULD4 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28298684 | 0.89 | KMT2A (0.52) | KMT2AHTR6LMNAMAPTHPGD | |
| SCHEMBL28051052 | 0.86 | ALDH1A1 (0.53) | PKMKMT2AHTR6LMNAMAPT | |
| SCHEMBL28297104 | 0.86 | KMT2A (0.62) | KMT2ALMNAMAPTTRIM24BRD1 | |
| SCHEMBL28297107 | 0.86 | MAPT (0.60) | PKMKMT2AHTR6LMNAMAPT | |
| SCHEMBL28298620 | 0.84 | HTT (0.57) | PKMHTR6LMNAMAPTHPGD | |
| SCHEMBL28298639 | 0.83 | BRD1 (0.46) | KMT2ALMNAMAPTTRIM24BRD1 | |
| SCHEMBL28051137 | 0.70 | HTT (0.61) | PKMKMT2ALMNAMAPTHPGD | |
| SCHEMBL19598935 | 0.68 | PKM (0.55) | PKMKMT2ALMNAMAPTHPGD | |
| SCHEMBL27651555 | 0.67 | ALDH1A1 (0.54) | KMT2ALMNAMAPTTRIM24BRD1 | |
| SCHEMBL27651556 | 0.67 | ALDH1A1 (0.60) | KMT2AHTR6LMNAMAPTTRIM24 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109851550-A | 7- aminocarbazole sulfamide derivative and its preparation method and application | 中国医学科学院医药生物技术研究所 | 2019-06-07 | — | — | CN | claimed |
| CN-109851550-A | 7- aminocarbazole sulfamide derivative and its preparation method and application | 中国医学科学院医药生物技术研究所 | 2019-06-07 | — | — | CN | disclosed |