Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD1 | O95696 | 8/20 | 0.46 |
| ▸ | BRPF1 | P55201 | 8/20 | 0.46 |
| ▸ | BRPF3 | Q9ULD4 | 6/20 | 0.46 |
| ▸ | BRD9 | Q9H8M2 | 2/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TRIM24 | O15164 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28298684 | 0.87 | KMT2A (0.52) | BRD1BRPF1BRPF3ALDH1A1KMT2A | |
| SCHEMBL28297104 | 0.87 | KMT2A (0.62) | BRD1BRPF1BRPF3ALDH1A1KMT2A | |
| SCHEMBL28298638 | 0.83 | PKM (0.45) | BRD1BRPF1BRPF3ALDH1A1KMT2A | |
| SCHEMBL28298620 | 0.82 | HTT (0.57) | ALDH1A1MAPTLMNAHTTTP53 | |
| SCHEMBL28297107 | 0.80 | MAPT (0.60) | ALDH1A1KMT2ATRIM24MAPTLMNA | |
| SCHEMBL27651556 | 0.77 | ALDH1A1 (0.60) | BRD1BRPF1BRPF3ALDH1A1KMT2A | |
| SCHEMBL27651555 | 0.74 | ALDH1A1 (0.54) | BRD1BRPF1BRPF3BRD4ALDH1A1 | |
| SCHEMBL27474093 | 0.72 | HPGD (0.56) | BRD1BRPF1BRPF3ALDH1A1KMT2A | |
| SCHEMBL28051052 | 0.69 | ALDH1A1 (0.53) | BRD1BRPF1BRPF3ALDH1A1KMT2A | |
| SCHEMBL23014626 | 0.69 | LMNA (0.71) | ALDH1A1KMT2AMAPTLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109851550-A | 7- aminocarbazole sulfamide derivative and its preparation method and application | 中国医学科学院医药生物技术研究所 | 2019-06-07 | — | — | CN | claimed |
| CN-109851550-A | 7- aminocarbazole sulfamide derivative and its preparation method and application | 中国医学科学院医药生物技术研究所 | 2019-06-07 | — | — | CN | disclosed |