Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | AKR1B10 | O60218 | 4/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 4/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 5/20 | 0.36 |
| ▸ | TTR | P02766 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methacrylic Acid SCHEMBL28172617 | 0.96 | THRB (0.39) | THRBHCAR2AKR1B10AKR1B1ALOX5 | |
| SCHEMBL4354447 | 0.86 | THRB (0.54) | THRBHCAR2AKR1B10AKR1B1ALOX5 | |
| Methacrylic Acid SCHEMBL9128151 | 0.84 | TSHR (0.51) | THRBHCAR2AKR1B10AKR1B1ALOX5 | |
| Methacrylic Acid SCHEMBL7262507 | 0.84 | THRB (0.56) | THRBHCAR2AKR1B10AKR1B1ALOX5 | |
| SCHEMBL150510 | 0.82 | LMNA (0.49) | THRBHCAR2AKR1B10AKR1B1ALOX5 | |
| SCHEMBL149640 | 0.81 | THRB (0.59) | THRBHCAR2AKR1B10AKR1B1ALOX5 | |
| Methacrylic Acid SCHEMBL8131805 | 0.80 | HCAR2 (0.49) | THRBHCAR2AKR1B10AKR1B1ALOX5 | |
| SCHEMBL31404677 | 0.80 | THRB (0.68) | THRBHCAR2AKR1B10AKR1B1ALOX5 | |
| SCHEMBL10426103 | 0.80 | THRB (0.68) | THRBHCAR2AKR1B10AKR1B1ALOX5 | |
| Ethyl Acetate SCHEMBL28298831 | 0.79 | THRB (0.43) | THRBLMNAHPGDSMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105792860-B | Reflective soft acrylic material with high refractive index and minimum | 诺华股份有限公司 | 2019-06-04 | — | — | CN | disclosed |