Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.45 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.45 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19911364 | 0.80 | MAPT (0.61) | ALDH1A1MAPTHPGDPKMKMT2A | |
| SCHEMBL594361 | 0.80 | ALDH1A1 (0.60) | ALDH1A1MAPTHPGDPKMKMT2A | |
| SCHEMBL211698 | 0.80 | L3MBTL1 (0.61) | ALDH1A1MAPTHPGDPKMKMT2A | |
| SCHEMBL19911377 | 0.80 | PKM (0.64) | ALDH1A1MAPTHPGDPKMKMT2A | |
| SCHEMBL19911380 | 0.80 | ALDH1A1 (0.56) | ALDH1A1MAPTHPGDPKMKMT2A | |
| SCHEMBL11050724 | 0.79 | ALDH1A1 (0.58) | ALDH1A1MAPTHPGDPKMKMT2A | |
| SCHEMBL19911367 | 0.78 | ALDH1A1 (0.57) | ALDH1A1MAPTHPGDPKMKMT2A | |
| SCHEMBL12732375 | 0.76 | ALDH1A1 (0.56) | ALDH1A1MAPTHPGDPKMKMT2A | |
| SCHEMBL15531972 | 0.76 | ALDH1A1 (0.56) | ALDH1A1MAPTHPGDPKMKMT2A | |
| SCHEMBL22449397 | 0.76 | ALDH1A1 (0.56) | ALDH1A1MAPTHPGDPKMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105622580-B | Benzimidazole as prolyl hydroxylase inhibitors | 詹森药业有限公司 | 2019-06-21 | — | — | CN | disclosed |