Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ORAI1 | Q96D31 | 3/20 | 0.47 |
| ▸ | ORAI2 | Q96SN7 | 3/20 | 0.47 |
| ▸ | ORAI3 | Q9BRQ5 | 3/20 | 0.47 |
| ▸ | TRPV6 | Q9H1D0 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | LPL | P06858 | 1/20 | 0.42 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | ACHE | P22303 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7930396 | 0.87 | ENPP2 (0.41) | ORAI1ORAI2ORAI3TRPV6CA2 | |
| SCHEMBL5586183 | 0.82 | ORAI1 (0.67) | ORAI1ORAI2ORAI3TRPV6CA2 | |
| Tolyl Boronic Acid SCHEMBL28299771 | 0.77 | CA2 (0.67) | ORAI1ORAI2ORAI3TRPV6CA2 | |
| SCHEMBL8170702 | 0.75 | CYP1A2 (0.33) | ORAI1ORAI2ORAI3TRPV6CA2 | |
| SCHEMBL14703738 | 0.74 | ENPP2 (0.46) | ORAI1ORAI2ORAI3CA2ENPP2 | |
| SCHEMBL5600076 | 0.72 | ORAI1 (0.58) | ORAI1ORAI2ORAI3TRPV6CA2 | |
| SCHEMBL16984910 | 0.71 | ENPP2 (0.39) | ORAI1ORAI2ORAI3CA2ENPP2 | |
| SCHEMBL28035120 | 0.71 | ENPP2 (0.39) | ORAI1ORAI2ORAI3CA2ENPP2 | |
| SCHEMBL3988450 | 0.71 | ENPP2 (0.39) | ORAI1ORAI2ORAI3CA2ENPP2 | |
| SCHEMBL2318890 | 0.71 | ENPP2 (0.39) | ORAI1ORAI2ORAI3CA2ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106132938-B | Tetrazolinone compound and use thereof | 住友化学株式会社 | 2019-05-17 | — | — | CN | disclosed |