Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.30 |
| ▸ | WNT3A | P56704 | 1/20 | 0.30 |
| ▸ | MPO | P05164 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14968784 | 0.75 | P2RX7 (0.43) | P2RX7HSP90AA1CYP19A1KDM4EMKNK1 | |
| SCHEMBL30711676 | 0.75 | PTPRA (0.47) | P2RX7EPHX1CYP1A2CYP2D6 | |
| SCHEMBL2176754 | 0.74 | P2RX7 (0.42) | P2RX7HSP90AA1CYP19A1KDM4EMKNK1 | |
| SCHEMBL2176759 | 0.74 | P2RX7 (0.42) | P2RX7HSP90AA1CYP19A1KDM4EMKNK1 | |
| Formamide SCHEMBL28321399 | 0.74 | P2RX7 (0.37) | P2RX7HSP90AA1KDM4EMPOCYP1A2 | |
| SCHEMBL27928045 | 0.71 | P2RX7 (0.40) | P2RX7HSP90AA1CYP19A1KDM4EFAAH | |
| SCHEMBL28092231 | 0.70 | L3MBTL1 (0.41) | P2RX7CYP19A1KDM4ECYP1A2CYP2D6 | |
| SCHEMBL4557709 | 0.68 | ALDH1A1 (0.44) | P2RX7CYP19A1KDM4EEPHX1CYP1A2 | |
| SCHEMBL2554967 | 0.67 | HSP90AA1 (0.38) | P2RX7HSP90AA1CYP19A1 | |
| SCHEMBL6711147 | 0.67 | EPHX1 (0.59) | EPHX1CYP1A2ADORA3CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105992767-B | WNT pathway modulators | 新加坡科技研究局 | 2019-06-21 | — | — | CN | disclosed |