Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.79 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | CXCR4 | P61073 | 10/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.53 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.53 |
| ▸ | CCR2 | P41597 | 1/20 | 0.53 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyridine SCHEMBL28217977 | 0.90 | SIGMAR1 (0.64) | SIGMAR1MEN1KMT2AALDH1A1CYP2C9 | |
| SCHEMBL83548 | 0.89 | SIGMAR1 (1.00) | SIGMAR1MEN1KMT2AALDH1A1CYP2C9 | |
| SCHEMBL152631 | 0.89 | SIGMAR1 (1.00) | SIGMAR1MEN1KMT2AALDH1A1CYP2C9 | |
| Benzene SCHEMBL27761330 | 0.89 | SIGMAR1 (1.00) | SIGMAR1MEN1KMT2AALDH1A1CYP2C9 | |
| SCHEMBL6138636 | 0.89 | SIGMAR1 (1.00) | SIGMAR1MEN1KMT2AALDH1A1CYP2C9 | |
| SCHEMBL276363 | 0.89 | SIGMAR1 (1.00) | SIGMAR1MEN1KMT2AALDH1A1CYP2C9 | |
| SCHEMBL11174968 | 0.87 | SIGMAR1 (0.89) | SIGMAR1MEN1KMT2AALDH1A1CYP2C9 | |
| Dalfampridine SCHEMBL28192260 | 0.87 | SIGMAR1 (0.70) | SIGMAR1MEN1KMT2AALDH1A1CYP2C9 | |
| SCHEMBL8145866 | 0.87 | SIGMAR1 (0.96) | SIGMAR1MEN1KMT2AALDH1A1CYP2C9 | |
| SCHEMBL7573306 | 0.87 | SIGMAR1 (0.96) | SIGMAR1MEN1KMT2AALDH1A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109761883-A | A kind of 4- carbamate-cinnamamide -4- benzyl piperidine coumpound and its preparation method and application | 南阳师范学院 | 2019-05-17 | — | — | CN | claimed |
| CN-116694374-A | System for synthesizing 5, 6-dihydro-2 (IH) -pyridone based on photo-thermal and zero pollution extraction | 常州大学 | 2023-09-05 | — | — | CN | disclosed |