Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.96 |
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.66 |
| ▸ | TSHR | P16473 | 1/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.66 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.66 |
| ▸ | CXCR4 | P61073 | 7/20 | 0.62 |
| ▸ | MC4R | P32245 | 1/20 | 0.62 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.61 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.61 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.61 |
| ▸ | CCR2 | P41597 | 1/20 | 0.61 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.61 |
| ▸ | DRD4 | P21917 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8145866 | 1.00 | SIGMAR1 (0.96) | SIGMAR1MEN1KMT2AALDH1A1CYP2C9 | |
| SCHEMBL9538814 | 0.98 | SIGMAR1 (0.92) | SIGMAR1MEN1KMT2AALDH1A1CYP2C9 | |
| SCHEMBL276363 | 0.98 | SIGMAR1 (1.00) | SIGMAR1MEN1KMT2AALDH1A1CYP2C9 | |
| SCHEMBL152631 | 0.98 | SIGMAR1 (1.00) | SIGMAR1MEN1KMT2AALDH1A1CYP2C9 | |
| SCHEMBL83548 | 0.98 | SIGMAR1 (1.00) | SIGMAR1MEN1KMT2AALDH1A1CYP2C9 | |
| SCHEMBL6138636 | 0.98 | SIGMAR1 (1.00) | SIGMAR1MEN1KMT2AALDH1A1CYP2C9 | |
| Benzene SCHEMBL27761330 | 0.98 | SIGMAR1 (1.00) | SIGMAR1MEN1KMT2AALDH1A1CYP2C9 | |
| Hydrochloric Acid SCHEMBL2223234 | 0.96 | SIGMAR1 (0.96) | SIGMAR1MEN1KMT2AALDH1A1CYP2C9 | |
| SCHEMBL7062479 | 0.96 | SIGMAR1 (0.96) | SIGMAR1MEN1KMT2AALDH1A1CYP2C9 | |
| SCHEMBL10063607 | 0.96 | SIGMAR1 (0.96) | SIGMAR1MEN1KMT2AALDH1A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3177598-B1 | MACROCYCLIC COMPLEXES, THEIR PROCESS OF PREPARATION AND USE AS PET IMAGING AGENTS | INST NAT SANTE RECH MED (FR) | 2019-08-28 | — | — | EP | disclosed |
| US-10351539-B2 | Macrocyclic complexes, their process of preparation and use as PET imaging agents | INSERM (Institut National de la Santé et de le Recherche Médicale) (FR) | 2019-07-16 | — | — | US | disclosed |
| US-20170210714-A1 | MACROCYCLIC COMPLEXES, THEIR PROCESS OF PREPARATION AND USE AS PET IMAGING AGENTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2017-07-27 | — | — | US | disclosed |
| US-20170210714-A1 | MACROCYCLIC COMPLEXES, THEIR PROCESS OF PREPARATION AND USE AS PET IMAGING AGENTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2017-07-27 | — | — | US | disclosed |
| WO-2016016272-A1 | MACROCYCLIC COMPLEXES, THEIR PROCESS OF PREPARATION AND USE AS PET IMAGING AGENTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2016-02-04 | — | — | WO | disclosed |
| EP-0815091-B1 | POLYAZACYCLOALKANE COMPOUNDS | NYCOMED IMAGING AS (NO) | 2002-06-12 | — | — | EP | disclosed |
| US-5705637-A | Polyazacycloalkane compounds | NYCOMED IMAGING AS (NO) | 1998-01-06 | — | — | US | disclosed |
| US-5677446-A | Polyazacycloalkane compounds | NYCOMED IMAGING AS (NO) | 1997-10-14 | — | — | US | disclosed |
| US-5631368-A | Polyazacycloalkane compounds | NYCOMED IMAGING AS (NO) | 1997-05-20 | — | — | US | disclosed |
| WO-1996028433-A1 | POLYAZACYCLOALKANE COMPOUNDS | NYCOMED IMAGING A.S (NO) | 1996-09-19 | — | — | WO | disclosed |
| EP-0255471-A1 | 1,4,7,10-Tetraazacyclododecane-derivatives | SCHERING AKTIENGESELLSCHAFT (DE) | 1988-02-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10351539-B2 | Macrocyclic complexes, their process of preparation and use as PET imaging agents | MPI, PAICS, TFEB | SIGMAR1 2616/4885MEN1 5/4885KMT2A 4024/4885 |
| US-20170210714-A1 | MACROCYCLIC COMPLEXES, THEIR PROCESS OF PREPARATION AND USE AS PET IMAGING AGENTS | MPI, PAICS, TFEB | SIGMAR1 2616/4885MEN1 5/4885KMT2A 4024/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.