Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 2/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28292973 | 0.73 | OPRD1 (0.43) | BRD4OPRD1OPRK1OPRM1ALDH1A1 | |
| SCHEMBL20508884 | 0.72 | MEN1 (0.45) | BRD4OPRD1OPRK1OPRM1ALDH1A1 | |
| SCHEMBL3763386 | 0.72 | MEN1 (0.45) | BRD4OPRD1OPRK1OPRM1ALDH1A1 | |
| SCHEMBL11260988 | 0.71 | BRD4 (0.50) | BRD4OPRD1OPRK1OPRM1ALDH1A1 | |
| SCHEMBL16136368 | 0.68 | FPR2 (0.48) | BRD4OPRD1OPRK1OPRM1ALDH1A1 | |
| SCHEMBL21238449 | 0.67 | GABRA1 (0.63) | OPRD1OPRK1ALDH1A1TDP1 | |
| SCHEMBL29706729 | 0.66 | HTR2A (0.38) | ALDH1A1HPGDCYP2D6 | |
| SCHEMBL16133639 | 0.65 | MAPT (0.46) | BRD4OPRD1OPRK1OPRM1ALDH1A1 | |
| Efetozole SCHEMBL2109012 | 0.65 | BRD4 (0.51) | BRD4OPRD1OPRK1OPRM1ALDH1A1 | |
| Efetozole SCHEMBL21698044 | 0.65 | BRD4 (0.51) | BRD4OPRD1OPRK1OPRM1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109776509-A | A kind of N- substituted imidazole formate ester derivative and application thereof | 成都安诺晨创医药科技有限公司 | 2019-05-21 | — | — | CN | disclosed |