Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.34 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.34 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | ACACA | Q13085 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28302149 | 0.74 | CA2 (0.43) | CACNA1BCA2KMT2AL3MBTL1ACACB | |
| SCHEMBL28302135 | 0.73 | LMNA (0.47) | CA2KMT2ALMNAALDH1A1ACACB | |
| SCHEMBL28302128 | 0.71 | CA2 (0.48) | SLC7A5CA2LMNANPSR1 | |
| SCHEMBL5913940 | 0.66 | GLS (0.46) | CA2ATMGLS | |
| SCHEMBL5913936 | 0.66 | GLS (0.46) | CA2ATMGLS | |
| SCHEMBL16112209 | 0.65 | CHRM5 (0.44) | POLBACACB | |
| SCHEMBL22232743 | 0.65 | RIPK1 (0.50) | ATMLMNASMN1; SMN2 | |
| SCHEMBL22456387 | 0.65 | RIPK1 (0.50) | ATMLMNASMN1; SMN2 | |
| SCHEMBL18921533 | 0.65 | RIPK1 (0.50) | ATMLMNASMN1; SMN2 | |
| SCHEMBL12318659 | 0.65 | GLS (0.49) | L3MBTL1GLS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109952298-A | Indole carboxamides analog derivative, preparation method and its application in medicine | 江苏恒瑞医药股份有限公司 | 2019-06-28 | — | — | CN | disclosed |