Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 6/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | ATM | Q13315 | 3/20 | 0.32 |
| ▸ | BLM | P54132 | 2/20 | 0.32 |
| ▸ | GSK3A | P49840 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.32 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28306158 | 0.75 | PKM (0.41) | KMT2AMEN1PKMALDH1A1NPC1 | |
| SCHEMBL28307342 | 0.70 | PKM (0.37) | KMT2AMEN1PKMALDH1A1ATM | |
| SCHEMBL28306384 | 0.68 | PKM (0.35) | KMT2AMEN1PKMALDH1A1ATM | |
| SCHEMBL3667953 | 0.66 | PKM (0.44) | KMT2APKMALDH1A1NPC1HTT | |
| SCHEMBL9202861 | 0.66 | PKM (0.44) | KMT2APKMALDH1A1NPC1HTT | |
| SCHEMBL2690381 | 0.64 | MAPT (0.44) | KMT2AMEN1PKMALDH1A1NPC1 | |
| SCHEMBL27952825 | 0.64 | CDK2 (0.55) | KMT2ACCNA2CDK2CCNA1MEN1 | |
| SCHEMBL11834710 | 0.63 | PKM (0.44) | KMT2APKMALDH1A1NPC1HTT | |
| SCHEMBL27930543 | 0.63 | PKM (0.44) | KMT2AMEN1PKMALDH1A1NPC1 | |
| SCHEMBL9465187 | 0.62 | PKM (0.44) | CCNA2CDK2CCNA1PKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109970633-A | Pyridine sulfone and its derivative, preparation method and application | 湖南化工研究院有限公司 | 2019-07-05 | — | — | CN | claimed |
| CN-109970633-A | Pyridine sulfone and its derivative, preparation method and application | 湖南化工研究院有限公司 | 2019-07-05 | — | — | CN | disclosed |