Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.34 |
| ▸ | LMNA | P02545 | 5/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3667953 | 0.82 | PKM (0.44) | PKMMAPTLMNAHTTSMN1; SMN2 | |
| SCHEMBL28307342 | 0.80 | PKM (0.37) | PKMMAPTLMNAHTTSMN1; SMN2 | |
| SCHEMBL9202861 | 0.79 | PKM (0.44) | PKMMAPTLMNAHTTSMN1; SMN2 | |
| SCHEMBL28306384 | 0.77 | PKM (0.35) | PKMMAPTLMNAHTTSMN1; SMN2 | |
| SCHEMBL2690381 | 0.77 | MAPT (0.44) | PKMMAPTLMNAHTTSMN1; SMN2 | |
| SCHEMBL11834710 | 0.76 | PKM (0.44) | PKMMAPTLMNAHTTSMN1; SMN2 | |
| SCHEMBL28306166 | 0.75 | KMT2A (0.38) | PKMMAPTLMNAHTTSMN1; SMN2 | |
| SCHEMBL1625081 | 0.74 | LMNA (0.55) | PKMMAPTLMNAHTTSMN1; SMN2 | |
| SCHEMBL8873122 | 0.74 | PKM (0.41) | PKMMAPTLMNAHTTSMN1; SMN2 | |
| SCHEMBL3674616 | 0.72 | PKM (0.46) | PKMMAPTLMNAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109970633-A | Pyridine sulfone and its derivative, preparation method and application | 湖南化工研究院有限公司 | 2019-07-05 | — | — | CN | claimed |
| CN-109970633-A | Pyridine sulfone and its derivative, preparation method and application | 湖南化工研究院有限公司 | 2019-07-05 | — | — | CN | disclosed |