Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 7/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28306384 | 0.88 | PKM (0.35) | PKMGAATDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL28306158 | 0.80 | PKM (0.41) | PKMGAATDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL28306167 | 0.78 | SMN1; SMN2 (0.45) | TDP1ALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL2690381 | 0.72 | MAPT (0.44) | PKMGAATDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL28306166 | 0.70 | KMT2A (0.38) | PKMTDP1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL3667953 | 0.70 | PKM (0.44) | PKMGAATDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9202861 | 0.70 | PKM (0.44) | PKMGAATDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL13275600 | 0.68 | PKM (0.40) | PKMGAATDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL28306160 | 0.68 | HTT (0.39) | GAATDP1ALDH1A1SMN1; SMN2GRIN2D | |
| SCHEMBL11834710 | 0.67 | PKM (0.44) | PKMGAATDP1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109970633-A | Pyridine sulfone and its derivative, preparation method and application | 湖南化工研究院有限公司 | 2019-07-05 | — | — | CN | claimed |
| CN-109970633-A | Pyridine sulfone and its derivative, preparation method and application | 湖南化工研究院有限公司 | 2019-07-05 | — | — | CN | disclosed |