Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | MGMT | P16455 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 6/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28306384 | 0.81 | PKM (0.35) | SMN1; SMN2MAPTMGMTLMNAHPGD | |
| SCHEMBL28307342 | 0.78 | PKM (0.37) | SMN1; SMN2MAPTMGMTLMNAHPGD | |
| SCHEMBL28306158 | 0.71 | PKM (0.41) | SMN1; SMN2MAPTLMNAKMT2AALDH1A1 | |
| SCHEMBL8562456 | 0.69 | CYP3A4 (0.43) | SMN1; SMN2MAPTMGMTLMNAHPGD | |
| SCHEMBL28306175 | 0.68 | MAPT (0.43) | SMN1; SMN2MAPTMGMTLMNAHPGD | |
| SCHEMBL27196616 | 0.66 | MAPT (0.49) | SMN1; SMN2MAPTMGMTLMNAHPGD | |
| SCHEMBL520852 | 0.66 | SMN1; SMN2 (0.44) | SMN1; SMN2MAPTLMNAHPGDKMT2A | |
| SCHEMBL202892 | 0.65 | MAPT (0.48) | SMN1; SMN2MAPTMGMTLMNAHPGD | |
| SCHEMBL8562265 | 0.65 | MAPT (0.48) | SMN1; SMN2MAPTMGMTLMNAHPGD | |
| Water SCHEMBL9043626 | 0.65 | TLR7 (0.41) | ALDH1A1NPSR1TLR8TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109970633-A | Pyridine sulfone and its derivative, preparation method and application | 湖南化工研究院有限公司 | 2019-07-05 | — | — | CN | disclosed |