Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | MGMT | P16455 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | BLM | P54132 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28307335 | 0.83 | HTT (0.38) | MAPTMGMTLMNAHPGDHTT | |
| SCHEMBL28307341 | 0.81 | HTT (0.45) | MAPTMGMTLMNAHPGDHTT | |
| SCHEMBL28307334 | 0.81 | TLR8 (0.37) | MAPTLMNAKMT2AHTTALDH1A1 | |
| SCHEMBL28306176 | 0.72 | KMT2A (0.37) | MAPTMGMTLMNAHPGDKMT2A | |
| SCHEMBL28307339 | 0.72 | MAPT (0.38) | MAPTLMNAHPGDKMT2AHTT | |
| SCHEMBL28307346 | 0.69 | PIN1 (0.42) | MAPTMGMTLMNAHPGDKMT2A | |
| SCHEMBL28307340 | 0.69 | MAPT (0.39) | MAPTLMNAHPGDKMT2AHTT | |
| SCHEMBL28306167 | 0.68 | SMN1; SMN2 (0.45) | MAPTMGMTLMNAHPGDKMT2A | |
| SCHEMBL27863332 | 0.68 | ALDH1A1 (0.44) | MAPTLMNAKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL28306205 | 0.67 | KMT2A (0.35) | MAPTLMNAKMT2AHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109970633-A | Pyridine sulfone and its derivative, preparation method and application | 湖南化工研究院有限公司 | 2019-07-05 | — | — | CN | claimed |
| CN-109970633-A | Pyridine sulfone and its derivative, preparation method and application | 湖南化工研究院有限公司 | 2019-07-05 | — | — | CN | disclosed |