Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.34 |
| ▸ | MEN1 | O00255 | 6/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 3/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 2/20 | 0.33 |
| ▸ | NOS1 | P29475 | 2/20 | 0.33 |
| ▸ | NOS2 | P35228 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28306160 | 0.77 | HTT (0.39) | KMT2AMEN1ALDH1A1RAB9ANOS3 | |
| SCHEMBL28307343 | 0.74 | BACE1 (0.43) | KMT2AMEN1ALDH1A1RAB9ANOS3 | |
| SCHEMBL28306387 | 0.72 | NOS2 (0.42) | KMT2AMEN1ALDH1A1NPC1RAB9A | |
| SCHEMBL3951456 | 0.68 | CCNA2 (0.61) | CCNA2CDK2CCNA1KMT2AMEN1 | |
| SCHEMBL28306171 | 0.67 | MAPT (0.38) | KMT2AMEN1ALDH1A1BLMCDK5 | |
| SCHEMBL10589352 | 0.64 | MEN1 (0.45) | CCNA2CDK2CCNA1KMT2AMEN1 | |
| SCHEMBL28306166 | 0.61 | KMT2A (0.38) | CCNA2CDK2CCNA1KMT2AMEN1 | |
| SCHEMBL5037025 | 0.60 | CDK2 (0.40) | CCNA2CDK2CCNA1KMT2AMEN1 | |
| SCHEMBL27465805 | 0.59 | MAPT (0.49) | KMT2AALDH1A1BLMMAPTLMNA | |
| SCHEMBL482011 | 0.59 | CYP11B2 (0.41) | CCNA2CDK2CCNA1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109970633-A | Pyridine sulfone and its derivative, preparation method and application | 湖南化工研究院有限公司 | 2019-07-05 | — | — | CN | claimed |
| CN-109970633-A | Pyridine sulfone and its derivative, preparation method and application | 湖南化工研究院有限公司 | 2019-07-05 | — | — | CN | disclosed |