Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 1/20 | 0.42 |
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | HRH2 | P25021 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | IKBKB | O14920 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28307343 | 0.91 | BACE1 (0.43) | NOS2TLR7MEN1KMT2ALMNA | |
| SCHEMBL28306160 | 0.85 | HTT (0.39) | NOS2MEN1KMT2ALMNAHTT | |
| SCHEMBL28306168 | 0.72 | CCNA2 (0.42) | NOS2MEN1KMT2ALMNAHTT | |
| SCHEMBL28306171 | 0.71 | MAPT (0.38) | MEN1KMT2ALMNAHTTL3MBTL1 | |
| SCHEMBL28307334 | 0.69 | TLR8 (0.37) | NOS2TLR7MEN1KMT2ALMNA | |
| SCHEMBL562804 | 0.68 | ALDH1A1 (0.41) | NOS2TLR7ALDH1A1 | |
| SCHEMBL12484988 | 0.67 | NOS2 (0.35) | NOS2TLR7MEN1KMT2ALMNA | |
| SCHEMBL16182532 | 0.67 | MAPT (0.41) | TLR7MEN1KMT2ALMNAHTT | |
| SCHEMBL563635 | 0.67 | GPR84 (0.39) | ESR1 | |
| SCHEMBL11238635 | 0.65 | KCNH2 (0.38) | NOS2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109970633-A | Pyridine sulfone and its derivative, preparation method and application | 湖南化工研究院有限公司 | 2019-07-05 | — | — | CN | claimed |
| CN-109970633-A | Pyridine sulfone and its derivative, preparation method and application | 湖南化工研究院有限公司 | 2019-07-05 | — | — | CN | disclosed |