Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL468460 | 0.96 | TSHR (0.44) | TSHRCYP3A4TDP1MAPTCACNA1B | |
| SCHEMBL28163090 | 0.82 | THRB (0.47) | TSHRCYP3A4TDP1MAPTCACNA1B | |
| SCHEMBL350218 | 0.81 | TSHR (0.36) | TSHRCYP3A4TDP1ALDH1A1MEN1 | |
| SCHEMBL4698282 | 0.80 | TSHR (0.50) | TSHRCYP3A4TDP1MAPTCACNA1B | |
| SCHEMBL3797444 | 0.79 | CYP3A4 (0.38) | TSHRCYP3A4TDP1MAPTCACNA1B | |
| SCHEMBL11805885 | 0.78 | THRB (0.41) | TSHRCYP3A4TDP1MAPTCACNA1B | |
| SCHEMBL9640142 | 0.78 | ALDH1A1 (0.31) | TSHRALDH1A1 | |
| SCHEMBL3834150 | 0.77 | TSHR (0.56) | TSHRCYP3A4TDP1MAPTCACNA1B | |
| SCHEMBL175301 | 0.77 | CYP3A4 (0.39) | TSHRCYP3A4TDP1MAPTCACNA1B | |
| SCHEMBL6418608 | 0.77 | TSHR (0.46) | TSHRCYP3A4TDP1MAPTCACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110105492-A | A kind of hydrophobic oleophobic preparation method of micro/nano level powder modifier and micro/nano level powder | 中国科学技术大学 | 2019-08-09 | — | — | CN | disclosed |
| CN-110038248-A | A method of anti-re-ignition ultra-fine dry powder extinguishing agent is prepared using polymer sol | 中国科学技术大学 | 2019-07-23 | — | — | CN | disclosed |