Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SDHB | P21912 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28307460 | 0.88 | SDHB (0.45) | SDHBLMNAHTTHPGDNPSR1 | |
| SCHEMBL30526106 | 0.83 | SDHB (0.59) | SDHBLMNAHTTHPGDNPSR1 | |
| SCHEMBL28307462 | 0.83 | SDHB (0.59) | SDHBLMNAHTTHPGDNPSR1 | |
| SCHEMBL28307456 | 0.83 | SDHB (0.43) | SDHBLMNAHTTHPGDNPSR1 | |
| SCHEMBL28306297 | 0.82 | ACHE (0.39) | SDHBHPGDL3MBTL1KMT2ASMN1; SMN2 | |
| SCHEMBL30526108 | 0.80 | SDHB (0.40) | SDHBLMNAHTTHPGDNPSR1 | |
| SCHEMBL29976590 | 0.76 | SDHB (0.71) | SDHB | |
| SCHEMBL20985740 | 0.76 | SDHB (0.71) | SDHB | |
| SCHEMBL28306298 | 0.74 | SDHB (0.50) | SDHBLMNAHTTHPGDNPSR1 | |
| SCHEMBL28307452 | 0.74 | SDHB (0.48) | SDHBLMNAHTTHPGDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110023292-A | Apoptosis inhibitor | 北京生命科学研究所 | 2019-07-16 | — | — | CN | disclosed |