Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SDHB | P21912 | 4/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 12/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 12/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28307460 | 0.83 | SDHB (0.45) | SDHBKMT2ALMNATP53HPGD | |
| SCHEMBL28307456 | 0.80 | SDHB (0.43) | SDHBMAPTKMT2ALMNATP53 | |
| SCHEMBL28307462 | 0.80 | SDHB (0.59) | SDHBMAPTKMT2ALMNATP53 | |
| SCHEMBL30526106 | 0.80 | SDHB (0.59) | SDHBMAPTKMT2ALMNATP53 | |
| SCHEMBL28306291 | 0.80 | SDHB (0.41) | SDHBKMT2ALMNATP53HPGD | |
| SCHEMBL28306297 | 0.79 | ACHE (0.39) | SDHBMAPTKMT2AHPGDSMN1; SMN2 | |
| SCHEMBL19805790 | 0.77 | SDHB (0.67) | SDHB | |
| Pyridine SCHEMBL28307454 | 0.77 | SDHB (0.44) | SDHBHCRTR1HCRTR2MAPTKMT2A | |
| SCHEMBL29976753 | 0.77 | SDHB (0.67) | SDHB | |
| SCHEMBL21019829 | 0.72 | SDHB (0.40) | SDHBKMT2ALMNATP53HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11725000-B2 | Apoptosis inhibitors | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2023-08-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11725000-B2 | Apoptosis inhibitors | BAX, SDHA, SDHB | SDHB 3/4885HCRTR1 3582/4885HCRTR2 3443/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.