Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.39 |
| ▸ | SDHB | P21912 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28307460 | 0.83 | SDHB (0.45) | SDHBKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL28306291 | 0.82 | SDHB (0.41) | SDHBKMT2AMEN1TDP1L3MBTL1 | |
| SCHEMBL28307456 | 0.80 | SDHB (0.43) | SDHBKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL28307462 | 0.80 | SDHB (0.59) | SDHBKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL30526106 | 0.80 | SDHB (0.59) | SDHBKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL30526108 | 0.79 | SDHB (0.40) | SDHBKMT2AMEN1MAPTHPGD | |
| SCHEMBL19805841 | 0.77 | SDHB (0.66) | SDHB | |
| SCHEMBL29976663 | 0.77 | SDHB (0.66) | SDHB | |
| SCHEMBL28306298 | 0.73 | SDHB (0.50) | SDHBKMT2AMAPTHPGDSMN1; SMN2 | |
| SCHEMBL21020405 | 0.73 | SDHB (0.41) | SDHBKMT2AMEN1L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110023292-A | Apoptosis inhibitor | 北京生命科学研究所 | 2019-07-16 | — | — | CN | disclosed |