SCHEMBL28307351

SCHEMBL28307351

O=C(O)c1ccc2cc3ccccc3cc2c1Br

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
WDR5 P61964 1/20 0.55
LDHA P00338 1/20 0.53
SOS1 Q07889 1/20 0.49
MEN1 O00255 3/20 0.49
KMT2A Q03164 3/20 0.49
RXFP1 Q9HBX9 1/20 0.49
ALDH1A1 P00352 6/20 0.48
KDM4E B2RXH2 4/20 0.48
HPGD P15428 4/20 0.48
HSD17B10 Q99714 3/20 0.48
GLA P06280 2/20 0.48
CYP1A2 P05177 2/20 0.48
CYP2C19 P33261 2/20 0.48
NR4A1 P22736 1/20 0.48
NR4A2 P43354 1/20 0.48
NR4A3 Q92570 1/20 0.48
GAA P10253 2/20 0.47
IDO1 P14902 1/20 0.46
LMNA P02545 1/20 0.44
ACMSD Q8TDX5 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL485599 0.85 WDR5 (0.68) WDR5LDHASOS1MEN1KMT2A
SCHEMBL28771671 0.85 PTPN1 (0.50) WDR5LDHAKDM4EHSD17B10GRIN2D
SCHEMBL9649985 0.81 WDR5 (0.69) WDR5LDHASOS1MEN1KMT2A
SCHEMBL28875087 0.80 ALDH1A1 (0.50) MEN1KMT2AALDH1A1KDM4EHPGD
SCHEMBL43510 0.80 KDM4E (0.60) WDR5LDHASOS1MEN1KMT2A
SCHEMBL29506855 0.80 KDM4E (0.60) WDR5LDHASOS1MEN1KMT2A
SCHEMBL15330092 0.80 LDHA (0.70) WDR5LDHASOS1MEN1KMT2A
SCHEMBL161027 0.80 WDR5 (0.52) WDR5LDHASOS1MEN1KMT2A
SCHEMBL7585579 0.80 WDR5 (0.61) WDR5LDHASOS1MEN1KMT2A
SCHEMBL31386625 0.79 KDM4E (0.58) WDR5LDHASOS1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109929094-A A kind of blue light frequency-doubling luminescent material and the preparation method and application thereof based on anthra sulphur dibenzofuran unit 华南理工大学 2019-06-25 CN disclosed