Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4A | P47712 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.35 |
| ▸ | ADA | P00813 | 1/20 | 0.34 |
| ▸ | RBP4 | P02753 | 1/20 | 0.34 |
| ▸ | P4HTM | Q9NXG6 | 3/20 | 0.33 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.33 |
| ▸ | KDM5A | P29375 | 2/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | P4HA1 | P13674 | 1/20 | 0.32 |
| ▸ | MIF | P14174 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7265607 | 0.84 | PLA2G4A (0.39) | PLA2G4AKDM4ESMYD3ADARBP4 | |
| SCHEMBL3690823 | 0.82 | PLA2G4A (0.39) | PLA2G4AKDM4ESMYD3RBP4P4HTM | |
| SCHEMBL151394 | 0.82 | SMYD3 (0.50) | PLA2G4AKDM4ESMYD3RBP4HCAR2 | |
| SCHEMBL28309917 | 0.82 | ADA (0.46) | SMYD3ADALMNATSHR | |
| SCHEMBL4901656 | 0.82 | PLA2G4A (0.39) | PLA2G4AKDM4ESMYD3RBP4P4HTM | |
| SCHEMBL4590582 | 0.82 | PLA2G4A (0.42) | PLA2G4AKDM4ESMYD3RBP4P4HTM | |
| SCHEMBL710279 | 0.79 | KDM5A (0.54) | PLA2G4AKDM4ESMYD3KDM5AKDM5B | |
| SCHEMBL24035826 | 0.77 | PLA2G4A (0.37) | PLA2G4AKDM4ESMYD3ADARBP4 | |
| SCHEMBL25235849 | 0.77 | CPB2 (0.47) | PLA2G4AKDM4ESMYD3HCAR2KDM5A | |
| SCHEMBL4738757 | 0.77 | PLA2G4A (0.40) | PLA2G4AKDM4ESMYD3RBP4KDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015009882-A2 | CYANO DERIVATIVES AND THEIR USES | THE HAMNER INSTITUTES (US) | 2015-01-22 | — | — | WO | disclosed |
| US-7763607-B2 | Pharmaceutical compositions comprising CBx cannabinoid receptor modulators and potassium channel modulators | SOLVAY PHARMACEUTICALS GMBH (DE) | 2010-07-27 | — | — | US | disclosed |
| US-20070254862-A1 | Pharmaceutical compositions comprising CBx cannabinoid receptor modulators and potassium channel modulators | SOLVAY PHARMACEUTICALS GMBH (DE) | 2007-11-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070254862-A1 | Pharmaceutical compositions comprising CBx cannabinoid receptor modulators and potassium channel modulators | CNR1, CNR2, KCNJ11 | PLA2G4A 872/4885KDM4E 782/4885SMYD3 1822/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.