Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 3/20 | 0.45 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 2/20 | 0.43 |
| ▸ | CASP7 | P55210 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28326140 | 0.75 | GRM5 (0.50) | GRM5 | |
| SCHEMBL17979380 | 0.69 | MCHR1 (0.66) | — | |
| SCHEMBL15005088 | 0.69 | PARP10 (0.46) | GRM5L3MBTL1NPC1SMN1; SMN2KMT2A | |
| SCHEMBL7512966 | 0.67 | GSK3A (0.33) | ALDH1A1NPC1KMT2AHSD17B10MEN1 | |
| SCHEMBL9396282 | 0.67 | MEN1 (0.54) | GRM5GRM3ALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL23895084 | 0.67 | BRD4 (0.46) | GRM5ALDH1A1CYP1A2L3MBTL1NPC1 | |
| SCHEMBL23258693 | 0.66 | L3MBTL1 (0.51) | ALDH1A1L3MBTL1NPC1SMN1; SMN2KMT2A | |
| SCHEMBL4337813 | 0.66 | MEN1 (0.68) | ALDH1A1CYP1A2L3MBTL1SMN1; SMN2KMT2A | |
| SCHEMBL29738155 | 0.66 | ADORA2B (0.40) | ALDH1A1NPC1SMN1; SMN2KMT2ARAB9A | |
| Ammonia Solution, Strong SCHEMBL16163964 | 0.65 | KMT2A (0.43) | GRM5GRM3ALDH1A1L3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106543145-B | C-Met kinases presses down agent 3- (4- fluorophenyl) pyrimidone -5- benzoic acid amides derivative, preparation method and application | 山西医科大学 | 2019-07-19 | — | — | CN | disclosed |