Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 5/20 | 0.38 |
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.38 |
| ▸ | GOT1 | P17174 | 1/20 | 0.38 |
| ▸ | KYAT1 | Q16773 | 1/20 | 0.38 |
| ▸ | KYAT3 | Q6YP21 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27929079 | 0.82 | SRD5A1 (0.39) | NOTUMCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL28735654 | 0.77 | NOTUM (0.36) | NOTUMAADATGOT1KYAT1KYAT3 | |
| SCHEMBL28491796 | 0.75 | CHRM2 (0.41) | NOTUMAADATGOT1KYAT1KYAT3 | |
| SCHEMBL27383076 | 0.74 | ACE (0.39) | NOTUM | |
| SCHEMBL7554141 | 0.74 | NOTUM (0.49) | NOTUMNPC1ALDH1A1 | |
| SCHEMBL4275949 | 0.74 | NOTUM (0.49) | NOTUMNPC1ALDH1A1 | |
| SCHEMBL27855041 | 0.73 | AADAT (0.37) | NOTUMAADATGOT1KYAT1KYAT3 | |
| SCHEMBL22292629 | 0.71 | NOTUM (0.53) | NOTUMCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL28384637 | 0.70 | NOTUM (0.39) | NOTUMAADATDRD2DRD4ALDH1A1 | |
| SCHEMBL27776797 | 0.70 | LMNA (0.52) | DRD2ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110194833-A | For causing the catalyst system of lactide ring-opening polymerisation and the preparation method of polylactic acid | 中国科学技术大学 | 2019-09-03 | — | — | CN | disclosed |