Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 6/20 | 0.39 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 4/20 | 0.36 |
| ▸ | DRD4 | P21917 | 3/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28317897 | 0.70 | NOTUM (0.38) | NOTUMAADATALDH1A1DRD2DRD4 | |
| SCHEMBL28491796 | 0.68 | CHRM2 (0.41) | NOTUMAADATALDH1A1DRD2DRD4 | |
| SCHEMBL27383076 | 0.67 | ACE (0.39) | NOTUM | |
| SCHEMBL28735654 | 0.67 | NOTUM (0.36) | NOTUMAADATALDH1A1DRD2DRD4 | |
| SCHEMBL4275949 | 0.67 | NOTUM (0.49) | NOTUMALDH1A1 | |
| SCHEMBL7554141 | 0.67 | NOTUM (0.49) | NOTUMALDH1A1 | |
| SCHEMBL27855041 | 0.66 | AADAT (0.37) | NOTUMAADATALDH1A1DRD2DRD4 | |
| SCHEMBL28280223 | 0.64 | ADRA2A (0.41) | NOTUMAADATDRD2DRD3 | |
| SCHEMBL27776797 | 0.64 | LMNA (0.52) | ALDH1A1DRD2DRD3 | |
| SCHEMBL15181288 | 0.63 | GAA (0.38) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114516813-A | Continuous flow preparation method of diclofenac sodium | 复旦大学 | 2022-05-20 | — | — | CN | claimed |
| CN-111100057-B | Method for synthesizing diclofenac sodium intermediate 1- (2, 6-dichlorophenyl) indoline-2-ketone | 天方药业有限公司 | 2021-06-11 | — | — | CN | claimed |
| CN-111100057-A | Method for synthesizing diclofenac sodium intermediate 1- (2, 6-dichlorophenyl) indoline-2-ketone | 天方药业有限公司 | 2020-05-05 | — | — | CN | claimed |
| CN-113429308-B | Synthesis process of diclofenac sodium | 安徽普利药业有限公司 | 2023-07-18 | — | — | CN | disclosed |
| CN-114539086-A | Method for synthesizing diclofenac sodium | 复旦大学 | 2022-05-27 | — | — | CN | disclosed |
| CN-114516813-A | Continuous flow preparation method of diclofenac sodium | 复旦大学 | 2022-05-20 | — | — | CN | disclosed |
| CN-113429308-A | Process for synthesizing diclofenac sodium | 安徽普利药业有限公司 | 2021-09-24 | — | — | CN | disclosed |
| CN-111100057-B | Method for synthesizing diclofenac sodium intermediate 1- (2, 6-dichlorophenyl) indoline-2-ketone | 天方药业有限公司 | 2021-06-11 | — | — | CN | disclosed |
| CN-111100057-B | Method for synthesizing diclofenac sodium intermediate 1- (2, 6-dichlorophenyl) indoline-2-ketone | 天方药业有限公司 | 2021-06-11 | — | — | CN | disclosed |
| CN-111100057-B | Method for synthesizing diclofenac sodium intermediate 1- (2, 6-dichlorophenyl) indoline-2-ketone | 天方药业有限公司 | 2021-06-11 | — | — | CN | disclosed |
| CN-111100057-A | Method for synthesizing diclofenac sodium intermediate 1- (2, 6-dichlorophenyl) indoline-2-ketone | 天方药业有限公司 | 2020-05-05 | — | — | CN | disclosed |
| CN-111100057-A | Method for synthesizing diclofenac sodium intermediate 1- (2, 6-dichlorophenyl) indoline-2-ketone | 天方药业有限公司 | 2020-05-05 | — | — | CN | disclosed |
| CN-111100057-A | Method for synthesizing diclofenac sodium intermediate 1- (2, 6-dichlorophenyl) indoline-2-ketone | 天方药业有限公司 | 2020-05-05 | — | — | CN | disclosed |