Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 5/20 | 0.45 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.43 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | EIF4E | P06730 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CDC25A | P30304 | 1/20 | 0.38 |
| ▸ | CDC25B | P30305 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28320570 | 0.90 | ALOX5 (0.47) | PIM1SHMT2SCN10AALOX5EIF4E | |
| SCHEMBL28320591 | 0.85 | XDH (0.43) | PIM1SCN10AEIF4ECYP19A1 | |
| SCHEMBL12989125 | 0.80 | SCN5A (0.47) | SCN10AALOX5KDM4EMAPTRAB9A | |
| SCHEMBL13281913 | 0.77 | KDM4E (0.68) | PIM1SHMT2SCN10AALOX5EIF4E | |
| SCHEMBL16399168 | 0.75 | ADORA1 (0.45) | PIM1SHMT2SCN10AALOX5EIF4E | |
| SCHEMBL28321645 | 0.74 | ALDH1A1 (0.53) | PIM1EIF4EKDM4EARRAB9A | |
| SCHEMBL23457475 | 0.73 | KDM4E (0.50) | EIF4EKDM4ERAB9A | |
| SCHEMBL29699367 | 0.73 | KDM4E (0.50) | EIF4EKDM4ERAB9A | |
| SCHEMBL9264337 | 0.73 | SCN10A (0.54) | PIM1SHMT2SCN10AALOX5KDM4E | |
| SCHEMBL9264332 | 0.73 | SHMT2 (0.49) | PIM1SHMT2SCN10AALOX5EIF4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105408325-B | cyanotriazole compounds | 大塚制药株式会社 | 2019-10-22 | — | — | CN | disclosed |