Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 2/20 | 0.41 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.41 |
| ▸ | EIF4E | P06730 | 2/20 | 0.40 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.40 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | LDHA | P00338 | 1/20 | 0.39 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28320520 | 0.85 | PIM1 (0.45) | PIM1EIF4ESCN10ACYP19A1 | |
| SCHEMBL28321645 | 0.83 | ALDH1A1 (0.53) | XDHPIM1EIF4EHSD17B1HSD17B2 | |
| SCHEMBL23457617 | 0.82 | XDH (0.52) | XDHPIM1PIM3KCNH2SCN10A | |
| SCHEMBL29699351 | 0.82 | XDH (0.52) | XDHPIM1PIM3KCNH2SCN10A | |
| SCHEMBL28321648 | 0.80 | IDO1 (0.43) | XDHPIM1SCN9AEIF4EHSD17B1 | |
| SCHEMBL28251098 | 0.80 | KDM4E (0.52) | XDHSCN9AEIF4EHSD17B1HSD17B2 | |
| SCHEMBL28321644 | 0.79 | KCNH2 (0.43) | XDHPIM1SCN9AEIF4EHSD17B1 | |
| SCHEMBL28320570 | 0.78 | ALOX5 (0.47) | PIM1EIF4ESCN10ACYP19A1GAA | |
| SCHEMBL16399094 | 0.77 | CTSS (0.44) | XDHPIM1SCN9AEIF4ESREBF2 | |
| SCHEMBL16400544 | 0.77 | ADORA1 (0.42) | XDHPIM1SCN9AEIF4EKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105408325-B | cyanotriazole compounds | 大塚制药株式会社 | 2019-10-22 | — | — | CN | claimed |
| CN-105408325-B | cyanotriazole compounds | 大塚制药株式会社 | 2019-10-22 | — | — | CN | disclosed |