Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Lb-100. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPP5C known ✓ | P53041 | 2/20 | 1.00 |
| ▸ | PPP2CA known ✓ | P67775 | 1/20 | 1.00 |
| ▸ | TFPI2 | P48307 | 9/20 | 1.00 |
| ▸ | NPY4R | P50391 | 1/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | GMNN | O75496 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | THPO | P40225 | 1/20 | 0.57 |
| ▸ | PPM1B | O75688 | 3/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.49 |
| ▸ | PPP1CC | P36873 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lb-100 SCHEMBL19501013 | 1.00 | TFPI2 (1.00) | TFPI2PPP5CPPP2CANPY4RKDM4E | |
| Lb-100 SCHEMBL26377801 | 1.00 | TFPI2 (1.00) | TFPI2PPP5CPPP2CANPY4RKDM4E | |
| Lb-100 SCHEMBL19512780 | 1.00 | TFPI2 (1.00) | TFPI2PPP5CPPP2CANPY4RKDM4E | |
| Lb-100 SCHEMBL12390164 | 1.00 | TFPI2 (1.00) | TFPI2PPP5CPPP2CANPY4RKDM4E | |
| Lb-100 SCHEMBL13311584 | 1.00 | TFPI2 (1.00) | TFPI2PPP5CPPP2CANPY4RKDM4E | |
| Lb-100 SCHEMBL9880148 | 1.00 | TFPI2 (1.00) | TFPI2PPP5CPPP2CANPY4RKDM4E | |
| SCHEMBL14135374 | 0.87 | TFPI2 (0.77) | TFPI2PPP5CPPP2CANPY4RKDM4E | |
| SCHEMBL2332631 | 0.86 | TFPI2 (0.77) | TFPI2PPP5CPPP2CANPY4RKDM4E | |
| SCHEMBL1572846 | 0.85 | TFPI2 (0.74) | TFPI2PPP5CPPP2CANPY4RKDM4E | |
| SCHEMBL12390209 | 0.85 | TFPI2 (0.74) | TFPI2PPP5CPPP2CANPY4RKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 726 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026100508-A1 | RESIN COMPOSITION, CURED PRODUCT, LAMINATE, METHOD FOR PRODUCING CURED PRODUCT, METHOD FOR PRODUCING LAMINATE, METHOD FOR PRODUCING SEMICONDUCTOR DEVICE, SEMICONDUCTOR DEVICE, AND RESIN | 富士フイルム株式会社 | 2026-05-15 | — | — | WO | claimed |
| US-20260083149-A1 | Coffee Fermentation Using Pichia Kluyveri and Lactiplantibacillus Plantarum | CHR. HANSEN A/S (DK) | 2026-03-26 | — | — | US | claimed |
| US-20260033129-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2026-01-29 | — | — | US | claimed |
| US-20260031929-A1 | ENCODING AND DECODING METHOD AND APPARATUS | HUAWEI TECH CO LTD (CN) | 2026-01-29 | — | — | US | claimed |
| EP-4662202-A1 | PYRIDINE AND DIHYDROPYRIDINE COMPOUNDS AND USES THEREOF | Clark Atlanta University, Inc. (US) | 2025-12-17 | — | — | EP | claimed |
| EP-4646271-A1 | SUBSTITUTED SPIROCYCLIC-PYRROLOQUINAZOLINONES AND SPIROCYCLIC-PIPERIDINOQUINAZOLINONES | Mirati Therapeutics, Inc. (US) | 2025-11-12 | — | — | EP | claimed |
| US-12463746-B2 | Encoding and decoding method and apparatus | HUAWEI TECHNOLOGIES CO., LTD. (CN) | 2025-11-04 | — | — | US | claimed |
| EP-4605853-A1 | RADIOFREQUENCY READING SYSTEM ON BOARD A TRANSPORT VEHICLE | COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) | 2025-08-27 | — | — | EP | claimed |
| EP-4602679-A1 | RADIOFREQUENCY READING SYSTEM ON BOARD A TRANSPORT VEHICLE | COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) | 2025-08-20 | — | — | EP | claimed |
| EP-4593619-A1 | COFFEE FERMENTATION USING PICHIA KLUYVERI AND LACTIPLANTIBACILLUS PLANTARUM | Chr. Hansen A/S (DK) | 2025-08-06 | — | — | EP | claimed |
| WO-2022125735-A1 | PROCESSES FOR MAKING PRMT5 INHIBITORS | PRELUDE THERAPEUTICS INCORPORATED (US) | 2022-06-16 | — | — | WO | claimed |
| EP-3999826-A1 | LOW THERMAL CAPACITY MICRO-BOLOMETER AND ASSOCIATED MANUFACTURING METHOD | LYNRED (FR) | 2022-05-25 | — | — | EP | claimed |
| CN-114385972-A | Parallel computing method for directly solving structured triangular sparse linear equation set | 北京科技大学 | 2022-04-22 | — | — | CN | claimed |
| EP-3337115-B1 | COMBINING DIFFERENT OFDM NUMEROLOGIES IN ONE BAND | ALCATEL LUCENT (FR) | 2022-03-30 | — | — | EP | claimed |
| EP-3212745-B1 | LUBRICANT FOR MARINE ENGINES | TOTAL MARKETING SERVICES (FR) | 2022-03-30 | — | — | EP | claimed |
| US-20220064249-A1 | COMPOUNDS, COMPOSITIONS, METHODS, AND USES FOR TREATING INSULIN RESISTANCE, TYPE 2 DIABETES AND METABOLIC SYNDROME | LINK THERAPEUTICS, LLC | 2022-03-03 | — | — | US | claimed |
| WO-2022037447-A1 | CODING METHOD AND APPARATUS AND DECODING METHOD AND APPARATUS | 华为技术有限公司 | 2022-02-24 | — | — | WO | claimed |
| CN-114075611-A | Double-target SARS-CoV-2 virus nucleic acid detection primer group, application and fluorescent kit | 华南理工大学 | 2022-02-22 | — | — | CN | claimed |
| CN-114079530-A | Encoding method and device | 华为技术有限公司 | 2022-02-22 | — | — | CN | claimed |
| US-20220050048-A1 | MICROPLATE READER | KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) | 2022-02-17 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260033129-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | LBR, LDLR, OPRD1 | PPP5C 4770/4885PPP2CA 4324/4885TFPI2 4690/4885 |
| US-20260083149-A1 | Coffee Fermentation Using Pichia Kluyveri and Lactiplantibacillus Plantarum | MGAM, LCT, NOTUM | PPP5C 2073/4885PPP2CA 1189/4885TFPI2 1452/4885 |
| US-20260031929-A1 | ENCODING AND DECODING METHOD AND APPARATUS | HBB, HBG1, HBG2 | PPP5C 4372/4885PPP2CA 4535/4885TFPI2 3677/4885 |
| US-20220064249-A1 | COMPOUNDS, COMPOSITIONS, METHODS, AND USES FOR TREATING INSULIN RESISTANCE, TYPE 2 DIABETES AND METABOLIC SYNDROME | INSR, IRS1, INSRR | PPP5C 2404/4885PPP2CA 778/4885TFPI2 582/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.