SCHEMBL283237

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15725834	0.89	ALDH1A1 (0.64)	ALDH1A1KMT2ALMNAMAPTMAPK1
	SCHEMBL4865184	0.84	HTR6 (0.62)	ALDH1A1LMNAMAPTMAPK1SMN1; SMN2
	SCHEMBL1613091	0.83	HTR6 (0.66)	ALDH1A1LMNAMAPTMAPK1SMN1; SMN2
	SCHEMBL520263	0.83	SLC6A5 (0.61)	ALDH1A1KMT2ALMNAMAPTMAPK1
	SCHEMBL29833031	0.83	SLC6A5 (0.61)	ALDH1A1KMT2ALMNAMAPTMAPK1
	SCHEMBL6982016	0.83	LMNA (0.56)	ALDH1A1KMT2ALMNAMAPTMAPK1
	SCHEMBL8715563	0.82	HTR6 (0.65)	ALDH1A1LMNAMAPTMAPK1SMN1; SMN2
	Hydrochloric Acid SCHEMBL3258618	0.82	HTR6 (0.65)	ALDH1A1LMNAMAPTMAPK1SMN1; SMN2
	SCHEMBL328460	0.81	ALDH1A1 (0.65)	ALDH1A1KMT2ALMNAMAPTMAPK1
	SCHEMBL21644501	0.81	ALDH1A1 (0.54)	ALDH1A1KMT2ALMNAMAPTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.