SCHEMBL28323924

SCHEMBL28323924

Nc1cccc(-c2ccc3c(c2-c2cccc(N)c2O)Cc2ccccc2-3)c1O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.47
NPC1 O15118 3/20 0.40
RAB9A P51151 3/20 0.40
ALDH1A1 P00352 3/20 0.40
KDM4E B2RXH2 2/20 0.40
MAPT P10636 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
LMNA P02545 1/20 0.40
HPGD P15428 1/20 0.40
HTR7 P34969 2/20 0.40
HTR2B P41595 2/20 0.40
PGR P06401 1/20 0.38
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
DRD2 P14416 2/20 0.35
ADRA1D P25100 1/20 0.35
HTR2A P28223 1/20 0.35
HTR2C P28335 1/20 0.35
ADRA1A P35348 1/20 0.35
ADRA1B P35368 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27449640 0.89 PNMT (0.54) PNMTNPC1RAB9AALDH1A1KDM4E
SCHEMBL28283976 0.84 PNMT (0.46) PNMTNPC1RAB9AALDH1A1KDM4E
SCHEMBL5160246 0.82 ALDH1A1 (0.46) PNMTNPC1RAB9AALDH1A1KDM4E
SCHEMBL30855380 0.81 PGR (0.43) PNMTNPC1RAB9AALDH1A1KDM4E
SCHEMBL3763958 0.80 PNMT (0.51) PNMTNPC1RAB9AALDH1A1KDM4E
SCHEMBL29687282 0.79 PNMT (0.44) PNMTNPC1RAB9AALDH1A1KDM4E
SCHEMBL19326641 0.79 PNMT (0.47) PNMTNPC1RAB9AALDH1A1KDM4E
SCHEMBL7724534 0.78 CA2 (0.43) PNMTNPC1RAB9AALDH1A1KDM4E
SCHEMBL30163133 0.78 PNMT (0.52) PNMTNPC1RAB9AALDH1A1KDM4E
Phenol SCHEMBL28634798 0.78 PNMT (0.53) PNMTNPC1RAB9AALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107001629-B Resin and photosensitive polymer combination 东丽株式会社 2019-09-24 CN claimed
CN-106795285-B Polyimide solution, heat-resistant nonwoven fabric, and method for producing same 东丽株式会社 2020-06-05 CN disclosed
CN-107001629-B Resin and photosensitive polymer combination 东丽株式会社 2019-09-24 CN disclosed