Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRK6 | P43250 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 4/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28598339 | 0.71 | MAOA (0.42) | PPARAKDM4EMAPK1NPSR1SMPD1 | |
| SCHEMBL28327634 | 0.71 | ALDH1A1 (0.47) | PPARAMGLLKDM4EMAPK1 | |
| SCHEMBL27816116 | 0.70 | BID (0.51) | PPARAKDM4E | |
| SCHEMBL6025704 | 0.70 | ALDH1A1 (0.46) | KDM4EMAPK1 | |
| SCHEMBL9642139 | 0.70 | HTT (0.41) | GRK6PPARAKDM4ESMPD1 | |
| SCHEMBL11001539 | 0.69 | FBP1 (0.39) | GRK6MGLLNPSR1 | |
| SCHEMBL21776644 | 0.67 | PTPN1 (0.42) | PPARAMGLLKDM4EMAPK1 | |
| SCHEMBL10829173 | 0.66 | PPARA (0.61) | PPARAKDM4EHDAC1HDAC6 | |
| SCHEMBL17867211 | 0.66 | KAT8 (0.43) | PPARAKDM4E | |
| SCHEMBL11107777 | 0.66 | THRB (0.35) | GRK6PPARATHRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110305143-A | A kind of furans [2,3-c] and pyridine derivate and its preparation method and application | 济南新科医药科技有限公司 | 2019-10-08 | — | — | CN | disclosed |