Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 4/20 | 0.48 |
| ▸ | HTR6 | P50406 | 4/20 | 0.48 |
| ▸ | HTR3E | A5X5Y0 | 3/20 | 0.48 |
| ▸ | HTR3B | O95264 | 3/20 | 0.48 |
| ▸ | HTR3D | Q70Z44 | 3/20 | 0.48 |
| ▸ | HTR3C | Q8WXA8 | 3/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.44 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 2/20 | 0.41 |
| ▸ | NCF1 | P14598 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7732043 | 0.87 | HTR3A (0.61) | HTR3AHTR6HTR3EHTR3BHTR3D | |
| Tert-Butyl Formate SCHEMBL28840344 | 0.85 | HTR6 (0.48) | HTR3AHTR6HTR3EHTR3BHTR3D | |
| Tert-Butyl Formate SCHEMBL27748489 | 0.85 | MAPT (0.49) | HTR3AHTR6HTR3EHTR3BHTR3D | |
| Tert-Butyl Formate SCHEMBL27944976 | 0.85 | MAPT (0.51) | HTR3AHTR6HTR3EHTR3BHTR3D | |
| Tert-Butyl Formate SCHEMBL27666679 | 0.84 | ALDH1A1 (0.46) | HTR3AHTR6HTR3EHTR3BHTR3D | |
| Tert-Butyl Formate SCHEMBL27730811 | 0.83 | TP53 (0.43) | HTR3AHTR6HTR3EHTR3BHTR3D | |
| Tert-Butyl Formate SCHEMBL28794458 | 0.82 | ADRB1 (0.43) | HTR3AHTR6HTR3EHTR3BHTR3D | |
| Tert-Butyl Formate SCHEMBL28332257 | 0.82 | HTR6 (0.40) | HTR3AHTR6HTR3EHTR3BHTR3D | |
| Tert-Butyl Formate SCHEMBL27751353 | 0.81 | KDM4E (0.42) | HTR3AHTR6HTR3EHTR3BHTR3D | |
| Tert-Butyl Formate SCHEMBL27615062 | 0.80 | ADRB1 (0.47) | HTR3AHTR6HTR3EHTR3BHTR3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110467615-A | Azolopyrimidines include its pharmaceutical composition and its preparation method and application | SICHUAN KELUN BOTAI BIOMEDICAL CO LTD | 2019-11-19 | — | — | CN | disclosed |