Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.60 |
| ▸ | KRAS | P01116 | 2/20 | 0.58 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.57 |
| ▸ | NT5E | P21589 | 1/20 | 0.56 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.55 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.55 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.55 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.52 |
| ▸ | IMPDH2 | P12268 | 4/20 | 0.52 |
| ▸ | FUT6 | P51993 | 2/20 | 0.52 |
| ▸ | GPR17 | Q13304 | 2/20 | 0.51 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.51 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.51 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.51 |
| ▸ | P2RY11 | Q96G91 | 1/20 | 0.51 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.51 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.51 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.51 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Guanosine Triphosphate SCHEMBL27608840 | 0.95 | TGM2 (0.66) | TGM2KRASFUT5NT5EP2RY6 | |
| Xylose SCHEMBL1422097 | 0.95 | TGM2 (0.67) | TGM2KRASFUT5NT5EP2RY6 | |
| Demannose SCHEMBL5163477 | 0.93 | TGM2 (0.66) | TGM2KRASFUT5NT5EP2RY6 | |
| Demannose SCHEMBL2182862 | 0.93 | TGM2 (0.66) | TGM2KRASFUT5NT5EP2RY6 | |
| Demannose SCHEMBL20746287 | 0.93 | TGM2 (0.66) | TGM2KRASFUT5NT5EP2RY6 | |
| Demannose SCHEMBL4290630 | 0.93 | TGM2 (0.66) | TGM2KRASFUT5NT5EP2RY6 | |
| Galactose SCHEMBL6046113 | 0.93 | TGM2 (0.66) | TGM2KRASFUT5NT5EP2RY6 | |
| Guanosine Triphosphate SCHEMBL29280175 | 0.92 | TGM2 (0.68) | TGM2KRASFUT5NT5EP2RY6 | |
| E626 SCHEMBL27748771 | 0.89 | NT5E (0.66) | TGM2KRASFUT5NT5EIMPDH2 | |
| Guanosine SCHEMBL28048641 | 0.89 | TGM2 (0.57) | TGM2KRASFUT5NT5EP2RY6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110536703-A | Use Anti-AXL antibodies-drug conjugate combination treatment | ADC THERAPEUTICS SA | 2019-12-03 | — | — | CN | disclosed |