Guanosine Triphosphate

Guanosine Triphosphate

SCHEMBL29280175

Nc1nc2c(ncn2[C@@H]2O[C@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)[C@@H](O)[C@H]2O)c(=O)[nH]1.O=CC(O)C(O)CO

nearest known ligand 0.68

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Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TGM2 P21980 1/20 0.68
KRAS P01116 5/20 0.65
NT5E P21589 1/20 0.64
FUT5 Q11128 1/20 0.64
P2RY6 Q15077 2/20 0.61
P2RY2 P41231 1/20 0.61
P2RY4 P51582 1/20 0.61
P2RX3 P56373 2/20 0.59
IMPDH2 P12268 5/20 0.59
ENPP1 P22413 2/20 0.57
P2RY1 P47900 2/20 0.57
P2RX1 P51575 1/20 0.57
P2RY11 Q96G91 1/20 0.57
P2RX4 Q99571 1/20 0.57
DCPS Q96C86 1/20 0.56
P2RY12 Q9H244 1/20 0.56
IMPDH1 P20839 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Guanosine Triphosphate SCHEMBL27608840 0.96 TGM2 (0.66) TGM2KRASNT5EFUT5P2RY6
Xylose SCHEMBL1422097 0.96 TGM2 (0.67) TGM2KRASNT5EFUT5P2RY6
Demannose SCHEMBL5163477 0.95 TGM2 (0.66) TGM2KRASNT5EFUT5P2RY6
Demannose SCHEMBL20746287 0.95 TGM2 (0.66) TGM2KRASNT5EFUT5P2RY6
Demannose SCHEMBL2182862 0.95 TGM2 (0.66) TGM2KRASNT5EFUT5P2RY6
Galactose SCHEMBL6046113 0.95 TGM2 (0.66) TGM2KRASNT5EFUT5P2RY6
Demannose SCHEMBL4290630 0.95 TGM2 (0.66) TGM2KRASNT5EFUT5P2RY6
Guanosine Triphosphate SCHEMBL28337848 0.92 TGM2 (0.60) TGM2KRASNT5EFUT5P2RY6
Gtp SCHEMBL17367368 0.91 TGM2 (0.81) TGM2KRASNT5EFUT5P2RY6
Gtp SCHEMBL5809658 0.91 TGM2 (0.81) TGM2KRASNT5EFUT5P2RY6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117701657-A Method for improving biological stability of DNA paper folding by enzymatic introduction of threose nucleic acid 南京大学 2024-03-15 CN disclosed